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Active substance(s): BIMATOPROST

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Bimatoprost 300 mcg/ml Eye Drops


Read all of this leaflet carefully before you start
using this medicine because it contains important
information for you.
• Keep this leaflet. You may need to read it again.
• If you have further questions, ask your doctor or
• This medicine has been prescribed for you only. Do
not pass it on to others. It may harm them, even if
their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor or
pharmacist. This includes any possible side effects
not listed in this leaflet. See section 4.

What is in this leaflet
1. What Bimatoprost is
and what it is used for
2. What you need to
know before you use
3. How to use
4. Possible side effects
5. How to store
6. Contents of the pack
and other information


pharmacist for advice
before taking any

What Bimatoprost
is and what it is
used for

Bimatoprost may get into
breast milk so you should
not breast-feed while you
are using Bimatoprost.

Bimatoprost is an
antiglaucoma preparation.
It belongs to a group of
medicines called

Driving and using
Your sight may become
blurred for a short time just
after using Bimatoprost.
You should not drive or
use machines until your
sight is clear again.

Bimatoprost is used to
reduce high pressure in
the eye. This medicine
may be used on its own or
with other drops called
beta-blockers which also
reduce pressure.

Important information
about some of the
ingredients of
Bimatoprost contains
benzalkonium chloride, a
preservative which may
cause eye irritation and
which can discolour soft
contact lenses. Avoid
contact with soft contact
lenses. Do not use the
drops when you are
wearing your lenses. Wait
15 minutes after using the
drops before you put your
lenses back in.

Your eye contains a clear,
watery liquid that feeds the
inside of the eye. Liquid is
constantly being drained
out of the eye and new
liquid is made to replace
this. If the liquid cannot
drain out quickly enough,
the pressure inside the
eye builds up. This
medicine works by
increasing the amount of
liquid that is drained. This
reduces the pressure
inside the eye. If the high
pressure is not reduced, it
could lead to a disease
called glaucoma and
eventually damage your


How to use
3 Bimatoprost

What you need to
know before you
use Bimatoprost

Always use this medicine
exactly as your doctor or
pharmacist has told you.
Check with your doctor or
pharmacist if you are not

Do not use Bimatoprost:
• if you are allergic
(hypersensitive) to
bimatoprost or any of
the other ingredients of
this medicine (listed in
section 6).
• if you have had to stop
using eye drops in the
past because of a side
effect of the preservative
benzalkonium chloride.

Bimatoprost should only
be applied to the eye. The
recommended dose is one
drop of Bimatoprost in the
evening, once daily in
each eye that needs

If you use Bimatoprost
with another eye medicine,
wait at least five minutes
between using
Bimatoprost and the other
eye medicine.

Warnings and
Talk to your doctor or
pharmacist before using

Talk to your doctor, if:
• You have any breathing
• You have liver or kidney
• You have had a cataract
surgery in the past.
• You have dry eye.
• You have or have had
any problems with your
cornea (front transparent
part of the eye).
• You wear contact lenses
(see “Important
information about some
of the ingredients of
• You have or have had
low blood pressure or
low heart rate.
• You have had a viral
infection or inflammation
of the eye.

Bimatoprost may cause
your eyelashes to darken
and grow, and cause the
skin around the eyelid to
darken too. The colour of
your iris may also go
darker over time. These
changes may be permanent.
The change may be more
noticeable if you are only
treating one eye.
Children and adolescents
Bimatoprost has not been
tested in children under
the age of 18 and
therefore Bimatoprost
should not be used by
patients under 18 years.
Other medicines and
Tell your doctor or
pharmacist if you are
taking, have recently taken
or might take any other

Instructions for use:

You must not use the
bottle if the tamper-proof
seal on the bottle neck is
broken before you first use
1. Wash your hands. Tilt
your head back and look
at the ceiling.

2. Gently pull down the
lower eyelid until there is a
small pocket.

3. Turn the bottle upside
down and squeeze it to
release one drop into each
eye that needs treatment.

4. Let go of the lower lid,
and close your eye for 30

Pregnancy, breast-feeding
and fertility
If you are pregnant or
breast-feeding, think you
might be pregnant or are
planning to have a baby,
ask your doctor or

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Do not use more than
once a day as the
effectiveness of treatment
may be reduced.

Continued on the next page >>

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Wipe off any excess that
runs down the cheek.

Side effects where the
frequency is unknown

To help prevent infections,
do not let the tip of the
bottle touch your eye or
anything else. Put the cap
back on and close the
bottle straight after you
have used it.

Affecting the body
• Symptoms of allergic
reaction (swelling,
redness of the eye and
rash of the skin)
• Asthma
• Worsening of asthma
• Worsening of the lung
diseases called
obstructive pulmonary
disease (COPD)
• Shortness of breath

If a drop misses your eye,
try again.

Affecting the eye
• Eyes appear sunken

If you use more
Bimatoprost than you
If you use more
Bimatoprost than you
should, it is unlikely to
cause you any serious
harm. Put your next dose
in at the usual time. If you
are worried, talk to your
doctor or pharmacist.

Reporting of side effects
If you get any side effects,
talk to your doctor or
pharmacist. This includes
any possible side effects
not listed in this leaflet.
You can also report side
effects directly via the
Yellow Card Scheme
yellowcard). By reporting
side effects you can help
provide more information
on the safety of this

If you forget to use
If you forget to use
Bimatoprost, use a single
drop as soon as you
remember, and then go
back to your regular
routine. Do not use a
double dose to make up
for a forgotten dose.

If you stop using
Bimatoprost should be
used every day to work
properly. If you stop using
Bimatoprost the pressure
inside your eye may go up,
therefore talk to your
doctor before stopping this
If you have any further
questions on the use of
this medicine, ask your
doctor or pharmacist.

Keep this medicine out of
the sight and reach of
This medicine does not
require any special
storage conditions.

Do not use this medicine
after the expiry date which
is stated on the bottle label
and the carton after EXP.
The expiry date refers to
the last day of that month.

4 Possible

You must throw away the
bottle, at the latest, four
weeks after you first
opened it, even if there are
still some drops left. This
will prevent infections. To
help you remember, write
down the date you opened
it in the space on the box.

Like all medicines, this
medicine can cause side
effects, although not
everybody gets them.

Very common side
effects (may affect more
than 1 in 10 people)

Medicines should not be
disposed of via
wastewater or household
waste. Ask your
pharmacist how to dispose
of medicines no longer
required. These measures
will help to protect the

Affecting the eye
• Longer eyelashes (up to
45% of people)
• Slight redness (up to
44% of people)
• Itchiness (up to 14% of

and other
6 pack

Common side effects
(may affect up to 1 in 10

Contents of the

Affecting the eye
• An allergic reaction in
the eye
• Tired eyes
• Sensitivity to light
• Darker skin colour
around the eye
• Darker eyelashes
• Pain
• A feeling that something
is in your eye
• Sticky eyes
• Darker iris colour
• Difficulty in seeing
• Irritation
• Burning
• Inflamed, red and itchy
• Tears
• Dryness
• Worsening of vision
• Blurred vision
• Swelling of the
see-through layer which
covers the surface of the
• Small breaks in the
surface of the eye, with
or without inflammation

What Bimatoprost
• The active substance is
bimatoprost. One ml of
solution contains 0.3 mg
bimatoprost. One drop
contains approximately
7.5 micrograms
• The other ingredients
are benzalkonium
chloride (preservative),
citric acid monohydrate,
disodium phosphate
heptahydrate, sodium
chloride, purified water
and sodium hydroxide or
hydrochloric acid.

Affecting the body
• Headaches
• An increase in blood-test
results that show how
your liver is working
• Increased blood
Uncommon side effects
(may affect up to 1 in 100

What Bimatoprost looks
like and contents of the
Bimatoprost is a clear,
colourless solution,
practically free from
particles in a pack
containing either 1 plastic
bottle or 3 plastic bottles
each with a screw cap.
Each bottle is
approximately half full and
contains either 2.5
millilitres or 3 millilitres of
solution. This is enough for
4 weeks’ usage.
Not all pack sizes may be

Marketing Authorisation
Holder and Manufacturer

Affecting the eye
• Cystoid macular
oedema (swelling of the
retina within the eye
leading to worsening
• Inflammation within the
• Retinal bleeding
• Swollen eyelids
• Eyelid twitching
• Eyelid has moved away
from surface of eye
• Skin redness around the

Marketing Authorisation
Sandoz Limited
Frimley Business Park,
Frimley, Camberley,
GU16 7SR
United Kingdom

S.C. Rompharm Company
Eroilor Street, no. 1A
Otopeni 075100, Ilfov.

Affecting the body
• Nausea
• Dizziness
• Weakness
• Hair growth around the


Aeropharm GmbH
D-07407 Rudolstadt

Very rare side effects
(may affect up to 1 in
10,000 people)


Lek Pharmaceuticals d.d.
Verovškova 57
1526 Ljubljana

In very rare cases, some
patients with severe
damage to the clear layer
at the front of the eye (the
cornea) have developed
cloudy patches on the
cornea due to calcium
build-up during treatment.

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to store
5 How

This leaflet was last
revised in 04/2016.


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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.