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ANGILOL/Propanolol 10, 40, 80, 160 mg Tablets
What is in your tablets?
The active ingredient of Angilol is propanolol BP.
Angilol is available in strengths of 10 mg, 40 mg, 80 mg and 160 mg.
Angilol 10 mg contains 10 mg propanolol BP and is a round pink film-coated tablet engraved Angilol 10.
Angilol 40 mg contains 40 mg propanolol BP and is a round pink film-coated tablet engraved Angilol 40.
Angilol 80 mg contains 80 mg propanolol BP and is a round pink film-coated tablet engraved Angilol 80.
Angilol 160 mg contains 160 mg propanolol BP and is a round pink film-coated tablet engraved Angilol 160.
Angilol tablets each contain lactose, gelatin, stearic acid, magnesium stearate, methylcellulose, hydroxypropylmethylcellulose,
diethylphthalate, E171, E120, E464.
Angilol tablets are available in containers of 50, 100, 250, 500 and 1,000 tablets, and in blister packs of 28 tablets.
The Manufacturer of Angilol is: DDSA Pharmaceuticals Ltd., Chatfield Road, off York Road, London SW11 3SE.
The Product Licence Holder of Angilol is: Chelonia Healthcare Limited, 11 Boumpoulinas, 3rd Floor, 1060 Nicosia, Cyprus
How does this medicine work?
Angilol belongs to a group of medicines known as the beta-blockers. They are useful for treatment of heart and circulation disorders.
If you are not sure why you have been prescribed Angilol, then please ask your doctor.
What are Angilol tablets for?
These tablets are used in the treatment of angina and the control of high blood pressure. It is also used to control anxiety and anxiety
causing palpitations and tremor (fine shaking, particularly of the hands). It is used to control irregular heartbeats and enlargement of the
heart. It is also used in the treatment of a condition known as phaeochromocytoma (which causes high blood pressure), and together with
other medicines in the management of disturbances of the thyroid gland.
Check before you take Angilol
Before taking this medicine, tell your doctor if you have ever had any unusual or allergic reactions to Propranolol or any of the other
ingredients of Angilol, or other beta-blocker medicines.
Also tell your doctor or pharmacist if you are allergic to any other substances such as foods, preservatives, or dyes.
Do not use Angilol if you are pregnant, breast feeding, or likely to become pregnant.
Do not use if you have asthma, difficulty in breathing or you have a history of wheezing.
The presence of other medical problems may affect the use of this medicine. Make sure, therefore, to tell your doctor or pharmacist if you
have any other medical problems, especially:
• If you suffer from bronchial spasm (persistent wheezing).
• If you suffer from heart failure and any other heart problems.

If you have diabetes.
If you have problems with your circulation.
If you have been told you have a phaeochromocytoma (which causes high blood pressure) and has not been treated.
If you have problems with your liver or kidneys.
If you have psoriasis.
If you have fasted for a prolonged length of time.

Can I drive whilst taking Angilol?
No, you should not drive whilst taking Angilol. The side effects of this medicine may affect concentration and the ability to drive,
therefore do not take charge of vehicles, or other means of transport or machinery, where loss of attention may lead to accidents.
Use in pregnancy
Angilol should not be used in pregnancy unless your doctor considers it is essential. Breast-feeding is not recommended.
Can you take Angilol with other medicines?
There are some medicines that can interfere with Angilol. It is very important to tell your doctor or pharmacist about all the
medicines that you are taking, whether or not any medicines were prescribed by your doctor or bought without a prescription
from the pharmacy or elsewhere.
Medicines which will interfere with the action of Angilol, or which can cause undesirable effects when taken with this medicine are:
verapamil (used in the treatment of heart conditions and high blood pressure); lignocaine (used to treat irregular heart beat); cimetidine
(used to treat stomach ulcers); rifampicin (used to treat certain infections); calcium channel antagonists (used to treat heart
conditions); chlorpromazine (used to treat mental illness); digital glycosides (used to treat heart conditions); clonidine, hydralazine
and other medicines used to treat high blood pressure; adrenaline; dihydropyridine derivatives (used in treatment of heart conditions);
prostaglandin synthetase inhibiting drugs; antidepressants (such as amitriptyline and fluvoxamine); barbiturates and
phenothiazines (sedatives like phenobarbitone and largactil); medicines used to treat diabetes (insulin, metformin); anaesthetics;
When and how to take Angilol
Angilol tablets should be taken by mouth and only in the doses prescribed by your doctor. Do not take more of it, and do not take it more
often or for a longer time than your doctor ordered.
Usual doses are stated below:
Remember Angilol tablets come in four strengths: 10 mg tablets, 40 mg tablets, 80 mg tablets & 160 mg tablets. Make certain you know
what strength of Angilol you have been prescribed.
In hypertension, the starting dose of Angilol should be 80 mg twice a day, to be increased by the same amount at weekly intervals, until
you doctor is satisfied with your response. Usually a response is seen within the dose range 160-320 mg per day (twice or four times the
initial dose). If your doctor sees fit a further reduction of blood pressure may be achieved when a medicine to encourage the passage of
urine and/or a blood pressure lowering drug is given in addition to Angilol.
In angina, anxiety and essential tremor, the starting dose is 40mg two or three times daily, to be increased by the same amount at weekly
intervals, until you doctor is satisfied with your response.
An adequate response in anxiety and essential tremor is usually seen in the range of 80-160 mg daily in divided doses. In angina the
dose to achieve adequate response will usually be 120-240 mg/day (in divided doses).
In cardiac dysrhythmias (alteration in heart beats), anxiety, tachycardia (rapid heartbeats), hypertrophic obstructive cardiomyopathy
(enlargement of the heart) and thyrotoxicosis (thyroid disease), most patients respond within the dosage range of 10-40 mg three or four
times a day.
In phaeochromocytoma (a condition which causes an increase in blood pressure) {when used only in conjunction with an alpha-receptor
blocking drug}:
Before operations: 60 mg daily for three days is recommended.
After operations: 30 mg daily.

Cardiac dysrhythmias (altered heart beats), phaeochromocytoma, thyrotoxicosis. The doses given are intended only as a guide:
Oral: 0.25-0.5 mg/kg bodyweight three or four times daily as required.
Fallot's Tetralogy (hole in the heart due to birth defect): The value of Angilol is confined mainly to certain types of this condition. It is also
useful for treatment of associated dysrhythmias (alteration in heart beats) and angina. Your doctor will determine the correct dosage, it is
usually up to 1 mg/kg bodyweight repeated three or four times daily as required.
The dosage will be determined by your doctor.
What to do if too many tablets are taken at the same time
If you accidentally take more tablets than recommended contact your nearest doctor or hospital casualty department at once. Take any
remaining tablets with you and keep in the original container or packaging so that they can be identified
What to do if you miss a dose
If you miss a dose, skip the missed dose and go back to your regular dosage schedule. Do not double the dose.
If you feel that this medicine is not working as well after you have taken it for a short time (1-2 weeks) do not increase the dose, instead
check with your doctor.
Your doctor will prescribe the lowest dose necessary to control your symptoms.
What side effects can Angilol cause?
The most common side effects are cold extremities, the feeling of sickness, insomnia, feeling more tired than usual (lethargy), and
diarrhoea. These effects soon pass away but can often be avoided by gradual reduction of dosage. Isolated case of rashes and bleeding
under the skin, sensations of pins and needles of the hands and feet have been reported. Very rarely slowing of the heart beat and a fall
in blood pressure may occur and then the drug should be withdrawn.
Other side effects include: bronchospasm (wheezing), dizziness, confusion, impotence, depression, low blood sugar levels, dry eyes and
a hyper thyroid gland which will be accompanied by shakiness, tiredness, swelling under the neck, sweating, diarrhoea, heart palpitations,
and unusual and irritable eye problems (e.g. dry eyes, staring eyes, sagging eye lids).
Tell your doctor if any of the above symptoms persist, or any other symptoms not mentioned become troublesome during treatment.
Storing your medicine
You must keep this medicine in a safe place where children cannot get hold of it. Your medicine could harm them.
Store below 25°C, in a dry place. Keep containers securely closed. Keep the tablets in the containers in which they were given to you.
On the label you will find the words "Expiry Date" followed by numbers indicating the day, month and year. This is the date when the
medicine is no longer fit for use. Do not use Angilol after this date, but return it to your doctor or pharmacist.
A reminder
REMEMBER this medicine is for you. Never give it to someone else, even if their symptoms are the same as yours.
This leaflet does not contain the complete information about your medicine. If you have any questions or are not sure about anything, ask
your doctor or pharmacist who have access to additional information.
This leaflet was revised in December 2008.

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