UK Edition. Click here for US version.
AMORIDE TABLETS 5MG
Active substance(s): AMILORIDE HYDROCHLORIDE
AMORIDE 5 mg
Read all of this leaflet carefully before you start
taking this medicine because it contains
important information for you.
- Keep this leaflet. You may need to read it again.
- If you have any further questions, ask your doctor
- This medicine has been prescribed for you
only. Do not pass it on to others. It may harm
them, even if their signs of illness are the same as
- If you get any side effects, talk to your doctor or
pharmacist. This includes any possible side
effects not listed in this leaflet. See section 4.
THIS LEAFLET CONTAINS
1. What Amoride is for
2. Before you take Amoride
3. How to take Amoride
4. Possible side effects
5. How to store Amoride
6. Further information
1. WHAT AMORIDE IS FOR
The name of your medicine is Amoride 5mg Tablets
(called Amoride in this leaflet). Amoride Tablets
contain the active ingredient amiloride hydrochloride
which belongs to a group of medicines known as
diuretics (water tablets).
Amoride can be used to stop the build-up of excess
water in your body. It does this by helping you pass
more than you usually do, without the loss of
potassium from the body.
Amoride is mainly used together with other medicines
that increase urine flow in order to conserve
Amoride can be used in the treatment of:
heart problems (congestive heart failure)
high blood pressure (hypertension)
fluid retention caused by liver problems (hepatic
If you are not sure why you have been prescribed
Amoride, please ask your doctor.
2. BEFORE YOU TAKE AMORIDE
DO NOT take Amoride and tell your doctor if you:
are allergic (hypersensitive) to amiloride
hydrochloride, or any of the other ingredients of
this medicine (listed in section 6)
have been told that you have high potassium
are taking any potassium containing medicines or
are not passing any water (urine)
have severe kidney problems or kidney failure.
This includes those caused by diabetes
have Addison’s disease (a disease of the adrenal
glands), which can cause weakness, tiredness,
weight loss and low blood pressure
Do not take this medicine if any of the above apply to
you. If you are not sure, talk to your doctor before
Warnings and precautions
The presence of other medical problems may affect
the use of this medicine. Talk to your doctor before
taking Amoride, if you:
have kidney problems
have liver problems
have too much acid in your blood. This can be
caused by diabetes or heart or lung diseases
If you are not sure if any of the above apply to you,
talk to your doctor or pharmacist before taking
Tests and Operations
Regular blood and urine tests may be needed to
monitor your electrolyte (e.g. potassium and sodium)
Tell your doctor or nurse you are taking Amoride if you
are going to have a glucose tolerance test. This is
because this medicine can affect the results and you
will need to stop taking it three days before your test.
If you are going to have an operation where you will be
given an anaesthetic, tell the doctor in charge that you
are taking Amoride.
Other medicines and Amoride
Tell your doctor or pharmacist if you are taking,
have recently taken or might take any other medicines.
This includes medicines you buy without a prescription
and herbal medicines. This is because Amoride can
affect the way some medicines work, and some
medicines can affect the way Amoride works.
In particular, tell your doctor if you are taking any of
medicines to treat high blood pressure, such as
Captopril and Enalapril (ACE inhibitors),
doxazosin, prazosin (alpha-blockers),
candesartan, losartan (angiotensin-II receptor
antagonists), aliskiren, clonidine, guanethidine,
hydralazine, methyldopa, minoxidil, moxonidine or
medicines to treat high blood pressure or chest
pain, such as atenolol, propranolol (betablockers), amlodipine, nifedipine (calcium-channel
blockers), glyceryl trinitrate, isosorbide
mononitrate (nitrates), moxisylyte
medicines to calm you down or help you sleep,
such as diazepam or nitrazepam
medicines known as Non-Steroidal
Anti-Inflammatory Drugs (NSAIDs) to treat pain
and swelling, such as ibuprofen, indometacin,
some medicines for depression or mental health
problems such as amitriptyline, dosulepin (tricyclic
antidepressants), phenelzine, tranylcypromine
(monoamine-oxidase inhibitors), chlorpromazine,
trifluoperazine (phenothiazines), lithium
some medicines to treat bacterial infections such
as lymecycline, oxytetracycline (tetracyclines),
some medicines used in the treatment of diabetes,
such as canagliflozin, chlorpropamide, diazoxide
some medicines to treat Parkinson’s disease,
such as levodopa, beneldopa, co-careldopa
ciclosporin or tacrolimus used to suppress the
immune system and stop the rejection of organs
cisplatin or aldesleukin used to treat types of
muscle relaxants such as baclofen or tizanidine
hormones, such as oestrogens, for contraception
or hormone replacement therapy
trilostane used for treating Cushing’s disease or
steroids, such as hydrocortisone or prednisolone,
to treat swelling and allergies
digoxin to treat heart failure
alprostadil to treat erectile dysfunction
carbamazpeine to treat epilepsy
pentamidine to treat microbial infections
carbenoxolone to treat mouth ulcers
Amoride does not cause loss of potassium from your
body as other water tablets do. Therefore, it is not
necessary for you to get extra potassium in your diet
or take supplements. Too much potassium could even
Amoride with food and alcohol
total Parenteral nutrition (intravenous
administration of nutrients)
AVOID ALCOHOL whilst taking this medicine
Pregnancy and breast-feeding
Talk to your doctor before taking this medicine if you
are pregnant, planning to become pregnant or are
Driving and using machines
Amoride is not likely to affect you being able to drive or
use any tools or machines.
Amoride Tablets contain lactose
If you have been told by your doctor that you have an
intolerance to some sugars, contact your doctor before
taking this medicinal product.
3. HOW TO TAKE AMORIDE
Always take this medicine exactly as your doctor has
told you. Check with your doctor or pharmacist if you
are not sure.
The dose will depend on your condition and may need
to be increased or decreased over time to control your
symptoms. You will be prescribed the lowest dose
necessary to control your symptoms. Do not take
more of it, and do not take it more often or for a longer
time than your doctor ordered.
The recommended dose is:
Initially 10 mg each day, as a single or divided dose.
This may be increased to a maximum of 20 mg per day
Amoride taken with other diuretics
Heart problems (congestive heart failure):
Initially 2.5 mg per day along with the other diuretic.
This may be increased to a maximum of 10 mg each
High blood pressure (hypertension):
The usual 2.5 mg per day along with other diuretic
each day. This may be increased to 10 mg each day
Liver cirrhosis with swelling of the abdomen
Initially 5 mg along with other diuretic each day. This
may be increased to a maximum of 10 mg each day.
Use in Children:
The use of Amoride is not recommended for children
Your doctor will decide how much Amoride you should
take. You may be given a lower dose depending on
how well your kidneys are working, your blood
electrolyte levels and your response to treatment.
If you take more Amoride than you should
If you take more tablets than recommended contact
your nearest doctor or hospital casualty department at
once. Take any remaining tablets with you and keep in
the original container or packaging so that they can be
If you feel this medicine is not working as well after
you have taken it for a short time (1-2 weeks) do not
increase the dose, instead check with your doctor.
If you forget to take Amoride
If you miss a dose, skip the missed dose and go back
to your regular dosage schedule. Do not take a double
dose (two doses at once) to make up for a forgotten
If you have any further questions on the use of this
medicine, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, this medicine can cause side
effects, although not everybody gets them.
If you have an allergic reaction to Amoride, see a
doctor straight away
An allergic reaction may include:
any kind of skin rash, flaking skin, boils or sore lips
sudden wheeziness, fluttering or tightness of the
chest or collapse
If you get any of the following side effects, stop
taking Amoride and see your doctor as soon as
chest pain including angina, unusual heart beats,
feeling dizzy, particularly when standing up
bleeding in the stomach. Signs include passing
yellowing of the skin and whites of the eyes
disease of the brain (encephalopathy)
problems with your sight, increased pressure in
pain while passing urine or spasms of the bladder
difficulty in breathing
Tell your doctor if you get any of these side
itching, mild skin rashes, hair loss
muscle cramps, joint pain, back, neck or shoulder
pain, pain in arms and legs
pins and needles in fingers and toes
restlessness, eating disorder, feeling nervous or
unable to sleep or feeling sleepy
changes in sexual drive and function, inability to
achieve or maintain an erection(impotence)
cough, blocked nose (nasal congestion)
ringing in the ears, a feeling of spinning
increase in the number of times and the amount of
water (urine) you pass. This may be because your
bladder is not emptying completely or due to the
weakness, loss of appetite, fatigue
feeling sick or being sick
thirst or dryness of mouth
diarrhoea or constipation
stomach pain or wind
heartburn, worsening of the effects of a stomach
changes in the results of blood tests. These
include changes in the way your liver is working,
changes in red or white blood cell levels or
changes in sodium levels or increased potassium
levels or increased acidic level in blood. Rise in
blood urea levels
Most of the side effects of Amoride are more likely to
occur in the elderly as they are usually more sensitive
to this medicine.
Reporting of side effects
If you get any side effects, talk to your doctor or
pharmacist. This includes any possible side effects not
listed in this leaflet. You can also report side effects
directly via the Yellow Card Scheme, website:
www.mhra.gov.uk/yellowcard. By reporting side
effects you can help provide more information on the
safety of this medicine.
5. HOW TO STORE AMORIDE
Keep this medicine out of the sight and reach of
Do not store above 25°C. Keep in the original package
or container. Keep the package or container tightly
closed and protect from light.
Do not use this medicine after the expiry date which is
stated on the package or container. The expiry date
refers to the last day of that month.
Do not throw away any medicines via wastewater or
household waste. Ask your pharmacist how to throw
away medicines you no longer use. These measures
will help protect the environment.
6. FURTHER INFORMATION
What Amoride contains
The active ingredient is amiloride hydrochloride. Each
tablet contains 5 mg of active substance.
The other ingredients are lactose, calcium hydrogen
phosphate, pregelatinised maize starch, maize starch,
What Amoride looks like and contents of the pack
Amoride 5 mg tablets are flat cream coloured tablets
engraved AMORIDE on one side and scored on the
Amoride is available in containers of 28, 30, 50, 56, 60,
84, 100, 250, 500 & 1000 tablets, and in blister packs
of 28, 30, 50, 56, 60, 100, 250, 500 & 1000 tablets.
Not all pack sizes may be marketed.
Marketing Authorisation Holder
Chelonia Healthcare Limited,
11 Boumpoulinas, 3rd Floor,
1060 Nicosia, Cyprus
Meridian Healthcare (UK) Limited,
Chatfield Road, off York Road,
London SW11 3SE
For any information about this medicine, please
contact the Marketing Authorisation Holder.
This leaflet was last revised in 07/2015.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.