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ALEXANDRIAN SENNA PODS BP

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SUMMARY OF PRODUCT CHARACTERISTICS

1

NAME OF THE MEDICINAL PRODUCT
Alexandrian Senna Pods

2

QUALITATIVE AND QUANTITATIVE COMPOSITION
Alexandrian Senna Pods 100% w/w

3

PHARMACEUTICAL FORM
Pods

4

CLINICAL PARTICULARS

4.1

Therapeutic indications
Used as a laxative.

4.2

Posology and method of administration
Adults, including the elderly:
Soak 6 to 8 senna pods in a glass of cold water for about 4 hours, drink the
infusion at bedtime.
In case of habitual constipation the number of pods may be increased or
diminished until satisfactory laxative action is brought into effect.
Children:
Prepare an infusion in cold water as above, care must be taken to use only
three or four senna pods, to which a little sugar may be added.

4.3

Contraindications
Where intestinal obstruction, abdominal pain, nausea or vomiting are present.

4.4

Special warnings and precautions for use
Excretion is by way of urine and faeces as well as by way of other secretions
including milk. Urine and Faeces may be coloured yellow or red in some
cases.

4.5

Interaction with other medicinal products and other forms of interaction
None.

4.6

Pregnancy and lactation
Not suitable for use during pregnancy and lactation without medical advice.

4.7

Effects on ability to drive and use machines
None known.

4.8

Undesirable effects
The constant use of purgative s to induce a regular daily habit may decrease
the sensitivity of the intestinal mucous membranes so that larger doses have to
be taken and the bowel fails to respond to normal stimuli. Thus the
redevelopment of a normal habit is prevented.

4.9

Overdose
Symptoms: Watery diarrhoea with excessive loss of water and electrolytes,
particularly potassium. Changes in the intestinal musculature associated with
malabsorption and dilation of the bowel, similar to ulcerative colitis an to
megacolon, have been observed after prolonged use of purgatives. Cardiac and
renal symptoms have also been reported as have melanosis Coli and
discoloration of urine when anthraquinone purgatives have been used.

5

PHARMACOLOGICAL PROPERTIES

5.1

Pharmacodynamic properties
Glycosides are hydrolysed by colonic bacteria in the intestinal tract and the
anthraquinones liberated into the colon where they probably stimulate the
myenteric plexus, cause direct stimulation and water electrolyte secretion.

5.2

Pharmacokinetic properties
The anthraquinones are partly absorbed in the colon. The absorbed material is
metabolised then excreted in the urine and mild if used during lactation. The
unabsorbed anthraquinones are excreted with the faeces.

5.3

Preclinical safety data
None stated.

6

PHARMACEUTICAL PARTICULARS

6.1

List of excipients
None.

6.2

Incompatibilities
None known.

6.3

Shelf life
3 years.

6.4

Special precautions for storage
None.

6.5

Nature and contents of container
Cardboard cartons 25 gm.

6.6

Special precautions for disposal
None stated.

7

MARKETING AUTHORISATION HOLDER
BRISTOL LABORATORIES,
UNIT 3, CANALSIDE,
NORTHBRIDGE ROAD,
BERKHAMSTED HP4 1EG,
UNITED KINGDOM

8

MARKETING AUTHORISATION NUMBER(S)
PL 17907/0381

9

DATE OF FIRST AUTHORISATION/RENEWAL OF THE
AUTHORISATION
30 March 1984 / 19 November 1999

10

DATE OF REVISION OF THE TEXT
11/01/2011

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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