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Active Substance: amprenavir
Common Name: amprenavir
ATC Code: J05AE05
Marketing Authorisation Holder: Glaxo Group Ltd.
Active Substance: amprenavir
Status: Withdrawn
Authorisation Date: 2000-10-20
Therapeutic Area: HIV Infections
Pharmacotherapeutic Group: Antivirals for systemic use

Therapeutic Indication

Agenerase, in combination with other antiretroviral agents, is indicated for the treatment of protease inhibitor (PI) experienced HIV-1 infected adults and children above the age of 4 years. Agenerase capsules should normally be administered with low dose ritonavir as a pharmacokinetic enhancer of amprenavir (see sections 4.2 and 4.5). The choice of amprenavir should be based on individual viral resistance testing and treatment history of patients (see section 5.1).
The benefit of Agenerase boosted with ritonavir has not been demonstrated in PI naïve patients (see section 5.1)

The marketing authorisation for Agenerase has been withdrawn at the request of the marketing authorisation holder.

Source: European Medicines Agency

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