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ACETAZOLAMIDE 250MG TABLETS
Active substance(s): ACETAZOLAMIDE / ACETAZOLAMIDE / ACETAZOLAMIDE
Moxaid 250mg Tablets
Read all of this leaflet carefully before you start taking this medicine.
Keep this leaflet. You may need to read it again.
If you have any further questions, ask your doctor or pharmacist.
This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same
If any of the side effects become serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
In this leaflet:
1. What Moxaid 250mg Tablets are and what they are used for
2. Before you take Moxaid 250mg Tablets
3. How to take Moxaid 250mg Tablets
4. Possible side effects
5. How to store Moxaid 250mg Tablets
6. Further information
1. WHAT MOXAID 250MG TABLETS ARE AND WHAT THEY ARE USED FOR
Moxaid 250mg Tablets contain the active substance Acetazolamide. This belongs to a group of medicines known as carbonic
Moxaid 250mg Tablets are used to treat:
• glaucoma (a condition of the eye), by reducing the pressure within the eye.
• abnormal retention of fluids (Moxaid 250mg Tablets acts as a diuretic)
• epilepsy (fits or convulsions).
2. BEFORE YOU TAKE MOXAID 250MG TABLETS
DO NOT take Moxaid 250mg Tablets if:
• you know you are allergic to sulphonamides, sulphonamide derivatives including acetazolamide or to any of the ingredients in
the medicine (listed in Section 6 at the end of this leaflet)
• you have severe liver problems
• you have or have ever had severe kidney problems
• you have a particular type of glaucoma known as chronic non congestive angle closure glaucoma (your doctor will be able to advise you)
• you have reduced function of the adrenal glands – glands above the kidneys - (also known as Addison’s disease)
• you have low blood levels of sodium and/or potassium or high blood levels of chlorine (your doctor will advise you)
Speak to your doctor if any of the above applies to you.
Take special care and speak to your doctor before taking Moxaid 250mg Tablets if:
• you have or have ever had kidney problems such as kidney stones
• you have lung problems such as chronic bronchitis or emphysema, which cause difficulty in breathing
• you are over the age of 65
• a small number of people being treated with anti-epileptics such as Acetazolamide have had thoughts of harming or killing
themselves, if at any time you have these thoughts, immediately contact your doctor.
Moxaid 250mg Tablets may affect some medical tests. If you visit a hospital or clinic for any medical tests, you should tell the doctor
concerned that you are taking Moxaid 250mg Tablets
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without
a prescription. The effects of any of these medicines may change, particularly if you are taking, or using, any of the following:
• medicines for your heart such as cardiac glycosides (e.g. digoxin)
• medicines to reduce blood pressure
• medicines to thin your blood (e.g. warfarin)
• medicines to lower the sugar in your blood (e.g. metformin, gliclazide)
• medicines for epilepsy or fits (in particular, phenytoin, primidone or carbamazepine or topiramate)
• drugs which interfere with folic acid, eg methotrexate, pyrimethamine, or trimethoprim
• steroids such as prednisolone
• aspirin and related medicines, eg salicylic acid or choline salicylate for mouth ulcers
• other drugs in the group of medicines called carbonic anhydrase inhibitors (e.g. dorzolamide or brinzolamide which are also
used to treat glaucoma)
• amphetamines (a stimulant), quinidine (treats an irregular heart beat), methenamine (prevents urine infections) or lithium (treats
severe mental problems)
• sodium bicarbonate therapy (used to treat high states of acid in your body)
• ciclosporin (used to suppress the immune system)
Pregnancy and breast feeding
Ask your doctor or pharmacist for advice before taking any medicines.
Moxaid 250mg Tablets SHOULD NOT be taken if you are pregnant, think you are pregnant or are planning to become pregnant. It
may be taken when breast feeding but only on the advice of the doctor.
Driving and using machines
If Moxaid 250mg Tablets make you feel drowsy or confused you should not drive or operate machines. Moxaid 250mg Tablets can
occasionally cause short-sightedness; if this happens and you feel that you can no longer drive safely, you should stop driving and
contact your doctor.
3. HOW TO TAKE MOXAID 250MG TABLETS
• Always take the number of tablets your doctor has told you to take. This information will also be on the label.
• Moxaid 250mg Tablets should be swallowed whole with a drink of water, just before or just after a meal. Do not chew or crush the tablets.
• The dose varies from person to person depending on their condition. Your doctor will decide on the most appropriate dose. If you
are not sure how many tablets to take or when to take them, ask your doctor or pharmacist.
Adults: 250mg-1000mg (1-4 tablets) every 24 hours, in divided doses
Retention of fluid:
Adults: starting dose is 250-375mg (1-1.5 tablets) once daily in the morning. Your doctor will adjust the dose and tell you how often
to take your dose.
Adults: 250-1000mg daily in divided doses
Children: the dose will depend on the bodyweight of the child, to be taken in divided doses. Dose should not be more than 750mg
(3 tablets) per day.
• Before starting and during treatment your doctor may monitor your blood to check that treatment with Moxaid 250mg Tablets is
suitable for you.
If you take more Moxaid 250mg Tablets than you should:
Get medical help immediately, either by calling your doctor or going to the nearest hospital casualty department. Take any
remaining tablets and this leaflet with you so that the medical staff know exactly what you have taken
If you forget to take your Moxaid 250mg Tablets
You should take it as soon as you remember. However, if this is within two hours of your next dose you should skip the missed
capsule and carry on taking the rest of your tablets as usual.
DO NOT take a double dose of tablets to make up the missed dose.
If you have any further questions about these tablets, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Moxaid 250mg Tablets can cause side effects, although not everybody gets them.
All medicines can cause allergic reactions although serious allergic reactions are very rare. Any sudden wheeziness,
difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body)
should be reported to a doctor immediately.
Common side effects (probably occuring in less than 1 in 10 people) are:
• feeling or being sick, loss of appetite, thirst, or a metallic taste in the mouth
• dizziness, loss of full control of arms or legs
• looking flushed
• a need to pass urine more often than normal
• tiredness or irritability
• feeling over-excited
• a tingling or numbness in the fingers or toes, or coldness in the extremities
Uncommon side effects (probably occuring in less than 1 in 100 people) are:
• drowsiness or confusion
• a loss of interest in sex
• ringing in the ears or difficulty in hearing
• temporary short-sightedness which subsides when the dosage is reduced or treatment is stopped.
Rare cases (probably occuring in less than 1 in 1000 people) of skin rashes including an increased sensitivity to sunlight have
been reported. If you experience any unusual skin rashes, inform your doctor.
Very rarely (probably occuring in less than 1 in 10000 people), Moxaid 250mg Tablets can affect the liver and kidneys. If you
experience pain in your lower back, pain or burning when you pass urine, have difficulty in passing urine, or you stop passing urine,
have blood in your urine, pale stools, or if your skin or eyes look slightly yellow, you should contact your doctor. You should also
contact your doctor if your stools are black or tarry, or if you notice blood in your stools.
Extremely rarely, Moxaid 250mg Tablets can affect the cells in your blood. This could mean that you are more likely to catch
infections and that your blood may not clot properly. If you have a sore throat or fever or you notice bruises or tiny red or purple
spots on your skin you should contact your doctor immediately. If your muscles feel weak or you have fits, you should see your
If you take Moxaid 250mg Tablets for a long time it can occasionally affect the amount of potassium, or sodium in your blood. Your
doctor will probably take blood tests to check that this does not happen. You might also experience bone thinning or the risk of
kidney stones with long-term therapy. High or low blood sugar levels may occasionally occur.
If any of the side effects becomes serious, or if you notice any side effects not listed in this leaflet, please tell your
doctor or pharmacist.
Reporting of side effects:
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this
leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.
By reporting side effects you can help provide more information on the safety of this medicine
5. HOW TO STORE MOXAID 250MG TABLETS
Do not store above 25 C. Store in the original container in order to protect from light and moisture.
Keep out of the sight and reach of children.
Do not use after the expiry date. This date is printed on your pack.
Medicines should not be disposed of via wastewater or household waste. Ask your
pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
This medicine is for you. Only a doctor can prescribe it for you. Never give this medicine to someone else; it could harm them,
even if their symptoms seem the same as yours.
6. FURTHER INFORMATION
What Moxaid 250mg Tablets Contain
The active substance is Acetazolamide. Each tablet contains 250mg acetazolamide.
The other ingredients are dicalcium phosphate, corn starch, magnesium stearate, sodium starch glycolate, povidone.
What Moxaid 250mg Tablets look like and contents of the pack
Moxaid 250mg Tablets are white, round, convex tablets with “FW 147” on one side and scored in quarters on the other. They usually
come in polypropylene bottles with polypropylene child resistant screw caps containing 112 tablets.
Marketing Authorisation Holder: Mercury Pharmaceuticals Ltd, Capital House, 85 King William Street, London EC4N 7BL, UK.
Manufacturer: Custom Pharmaceuticals Limited, Conway Street, Hove, East Sussex, BN3 3LW, UK.
This leaflet was last revised in September 2014.
Moxaid is a trademark of Amdipharm International Limited
Date of Approval:
To be implemented by:
Moxaid 250mg Tabs x 112
XXXXXXLF Moxaid Tabs v1_3
Quark Xpress 9
Minimum Font Size & Typeface:
8.5pt Swiss 721BT
190 x 297mm
Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.