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Piperazine Side Effects

Applies to piperazine: oral syrup, oral tablet

Along with its needed effects, piperazine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking piperazine:


  • Blurring of vision
  • clumsiness
  • crawling or tingling feeling of the skin
  • fever
  • irregular, twisting movement, especially of the face, arms, and legs
  • joint pain
  • skin rash or itching

Some side effects of piperazine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less Common

  • Abdominal or stomach cramps or pain
  • diarrhea
  • dizziness
  • drowsiness
  • headache
  • muscle weakness
  • nausea or vomiting
  • tremors

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.