Skip to Content

Oxymetazoline / tetracaine nasal Side Effects

Applies to oxymetazoline / tetracaine nasal: nasal solution

Along with its needed effects, oxymetazoline / tetracaine nasal may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking oxymetazoline / tetracaine nasal:

Less common
  • Bloody nose
  • blurred vision
  • chest pain or discomfort
  • difficulty swallowing
  • dizziness
  • headache
  • lightheadedness, dizziness, or fainting
  • nervousness
  • pounding in the ears
  • shortness of breath
  • slow or fast, irregular heartbeat
  • ulcers in the nose
  • unusual tiredness
Incidence not known
  • Bluish-colored lips, fingernails, or palms
  • cough
  • dark urine
  • difficulty breathing
  • dizziness or lightheadedness
  • fever
  • hives or welts, itching, or skin rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • noisy breathing
  • pale skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rapid heart rate
  • redness of the skin
  • sore throat
  • tightness in the chest
  • unusual bleeding or bruising

Get emergency help immediately if any of the following symptoms of overdose occur while taking oxymetazoline / tetracaine nasal:

Symptoms of overdose
  • Blurred or loss of vision
  • chest pain or discomfort
  • confusion
  • difficulty in speaking
  • disturbed color perception
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • double vision
  • fainting
  • fast, slow, or irregular heartbeat
  • halos around lights
  • headache
  • inability to move the arms, legs, or facial muscles
  • inability to speak
  • lightheadedness
  • nausea
  • nervousness
  • night blindness
  • no blood pressure or pulse
  • overbright appearance of lights
  • pain or discomfort in the arms, jaw, back, or neck
  • pounding in the ears
  • slow speech
  • stopping of heart
  • stuffy nose
  • sweating
  • tunnel vision
  • unconsciousness
  • unusual tiredness or weakness
  • vomiting

Some side effects of oxymetazoline / tetracaine nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings in the nose
  • change in taste
  • loss of taste
  • sore throat
  • stuffy or runny nose
  • watering of the eyes

Some side effects of oxymetazoline / tetracaine nasal may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

More about oxymetazoline/tetracaine nasal

Consumer resources

Other brands: Kovanaze

Professional resources

Related treatment guides

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.