Skip to Content

Lyme disease vaccine Side Effects

Applies to lyme disease vaccine: intramuscular suspension

Along with its needed effects, lyme disease vaccine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking lyme disease vaccine:

More common
  • Numbness
  • tingling
  • unusual tiredness or weakness
Less common
  • Bone pain
  • chills
  • cough
  • fever
  • muscle aches
  • runny or stuffy nose
  • shivering
  • skin rash, itching, redness, swelling, or other sign of irritation not present before vaccination
  • sneezing
  • sore throat
  • sweating
  • Difficulty swallowing
  • dizziness
  • fast heartbeat
  • headache, severe
  • puffiness or swelling around eyelids
  • shortness of breath

Some side effects of lyme disease vaccine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Back pain
  • pain in joints and/or muscles
Less common
  • Depression
  • diarrhea
  • dizziness
  • feeling unusually cold

Some side effects of lyme disease vaccine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.