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Edetate Calcium Disodium Side Effects

Medically reviewed by Drugs.com. Last updated on Jun 10, 2024.

Applies to edetate calcium disodium: parenteral injection.

Important warnings This medicine can cause some serious health issues

    Fatality Risk
  • Risk of potentially fatal toxic effects.b  (See Fatality Risk and also see Renal Effects under Cautions.)

  • Possible lethal increase in intracranial pressure following IV infusion in patients with lead encephalopathy and cerebral edema.b Manufacturer recommends IM administration in this patient population.b If administered IV, avoid rapid infusion.b  (See Administration under Dosage and Administration and see Fatality Risk under Cautions.)

  • Follow dosage schedule; do not exceed recommended daily dose.b

    Encephalopathy Risk
  • Lead encephalopathy occurs rarely in adults; occurs more often in pediatric patients, in whom encephalopathy may be incipient and overlooked and results in high mortality rate.b

Side effects include:

Injection site pain.

For healthcare professionals

Applies to edetate calcium disodium: compounding powder, injectable solution.

Metabolic

Cardiovascular

Gastrointestinal

Genitourinary

Renal

Hematologic

Hepatic

Increases in SGOT and SGPT usually return to normal within 48 hours after treatment discontinuation.[Ref]

Nervous system

Dermatologic

Other

Musculoskeletal

Immunologic

Local

References

1. Cerner Multum, Inc. "Australian Product Information."

2. (2017) "Product Information. Calcium Disodium Versenate (edetate calcium disodium)." Medicis Pharmaceutical Corporation

Further information

Edetate calcium disodium side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.