Skip to main content

Antibiotic Plus Pain Relief

Generic name: neomycin sulfate, polymyxin b sulfate, and pramoxine hydrochloride
Dosage form: cream
Drug class: Topical antibiotics

Medically reviewed by Last updated on Aug 23, 2021.

Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

Drug Facts

Active ingredients
(each gram contains)
Neomycin sulfate 3.5 mg First aid antibiotic
Polymyxin B sulfate 10,000 units First aid antibiotic
Pramoxine HCl 10 mg External analgesic


first aid to help prevent infection and for the temporary relief of pain or discomfort in minor:

  • cuts
  • scrapes
  • burns


For external use only

Do not use

  • in the eyes
  • over large areas of the body
  • if you are allergic to any of the ingredients

Ask a doctor before use if you have

  • deep or puncture wounds
  • animal bites
  • serious burns

Stop use and ask a doctor if

  • condition persists or gets worse
  • condition persists for more than 7 days
  • condition clears up and occurs again within a few days
  • a rash or other allergic reaction develops

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.


  • adults and children 2 years of age and older:
    • clean the affected area
    • apply a small amount of this product (an amount equal to the surface area of the tip of a finger) on the area 1 to 3 times daily
    • may be covered with a sterile bandage
  • children under 2 years of age: consult a doctor

Other information

  • To open: unscrew cap, pull tab to remove foil seal.
  • store at 20°-25°C (68°-77°F)
  • See carton or tube crimp for lot number and expiration date.

Inactive ingredients

emulsifying wax, methylparaben, mineral oil, propylene glycol, purified water, white petrolatum


Call 1-877-745-6888

Distributed by:
Phoenix Global Supply Group, Inc.
White Plains, NY 10604


Cream + Pain Relief
Neomycin Sulfate • Polymyxin B Sulfate • Pramoxine HCl

First Aid Antibiotic / Pain Relieving Cream

Maximum Strength

NET WT 1 oz (28.4 g)

Antibiotic Plus Pain Relief
neomycin sulfate, polymyxin b sulfate, and pramoxine hydrochloride cream
Product Information
Product Type HUMAN OTC DRUG Item Code (Source) NDC:52426-220
Route of Administration TOPICAL DEA Schedule
Active Ingredient/Active Moiety
Ingredient Name Basis of Strength Strength
Neomycin Sulfate (Neomycin) Neomycin Sulfate 3.5 mg in 1 g
Polymyxin B Sulfate (Polymyxin B) Polymyxin B Sulfate 10000 [iU] in 1 g
Pramoxine Hydrochloride (Pramoxine) Pramoxine Hydrochloride 10 mg in 1 g
Inactive Ingredients
Ingredient Name Strength
mineral oil
propylene glycol
Product Characteristics
Color WHITE Score
Shape Size
Flavor Imprint Code
# Item Code Package Description
1 NDC:52426-220-05 1 TUBE (TUBE) in 1 CARTON
1 14.2 g in 1 TUBE
2 NDC:52426-220-06 1 TUBE (TUBE) in 1 CARTON
2 28.4 g in 1 TUBE
Marketing Information
Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date
OTC MONOGRAPH FINAL part333B 09/23/2010
Labeler - Phoenix Global Supply Group, Inc. (843189908)
Name Address ID/FEI Operations
SGS Life Science Services 093840643 ANALYSIS
Name Address ID/FEI Operations
Axellia Pharmaceuticals ApS 305814345 MANUFACTURE
Name Address ID/FEI Operations
Pharmacia and UpJohn Company 829076566 MANUFACTURE
Name Address ID/FEI Operations
Syn-Tech Chem. & Pharm. Co., Ltd. 656002532 API MANUFACTURE
Phoenix Global Supply Group, Inc.

More about Antibiotic Plus Pain Relief (neomycin / polymyxin b / pramoxine topical)

Patient resources

Related treatment guides