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Botulinum toxin type b Pregnancy and Breastfeeding Warnings

Botulinum toxin type b is also known as: Myobloc

Botulinum toxin type b Pregnancy Warnings

Animal reproduction studies have not been conducted. It is not known if this drug can cause fetal harm when administered to a pregnant woman or affect reproduction capacity. There are no controlled data in human pregnancy.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Use is not recommended unless clearly needed

US FDA pregnancy category: C

See references

Botulinum toxin type b Breastfeeding Warnings

Benefit should outweigh risk

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

No data exist on the medical use of this drug during breastfeeding, although medical use is not expected to produce measurable blood levels and therefore it would not be expected to be available for secretion into breast milk.

There is a report of a mother who contracted botulism and successfully breastfed her infant. On admission to the hospital, type A botulinum toxin was detected in her blood and stools; none was detected in the infant's stools. The mother was treated with 2 vials of trivalent botulism antitoxin (IV and IM). A milk sample obtained 4 hours after administration of the antitoxin had no detectable botulinum toxin or botulism organisms.

See references

References for pregnancy information

  1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  2. "Product Information. Myobloc (botulinum toxin type B)" Elan Pharmaceuticals, S. San Francisco, CA.

References for breastfeeding information

  1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  2. "Product Information. Myobloc (botulinum toxin type B)" Elan Pharmaceuticals, S. San Francisco, CA.
  3. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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