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Cerliponase Alfa


(ser LIP oh nase AL fa)

Index Terms

  • Brineura

Dosage Forms

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Solution, Injection [preservative free]:

Brineura: 150 mg/5 mL (15 mL)

Brand Names: U.S.

  • Brineura

Pharmacologic Category

  • Hydrolytic Lysosomal N-terminal Tripeptidyl Peptidase

Use: Labeled Indications

Neuronal ceroid lipofuscinosis type 2: Indicated to delay the loss of ambulation in symptomatic pediatric patients ≥3 years with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2)


Acute intraventricular access device-related complications (eg, leakage, device failure, device-related infection), ventriculoperitoneal shunts

Drug Interactions

There are no known significant interactions.