Vascular Risk Factors Tied to Increased Incontinence Risk
THURSDAY, March 8, 2018 -- Many factors, including vascular risk factors, may play a role in the development of urgency urinary incontinence (UUI) in older men and women, according to a study published online March 7 in the BJU International.
Alex Tsui, from King's College Hospital in London, and colleagues analyzed data from 1,762 participants from the Medical Research Council National Survey for Health and Development birth cohort who answered the International Consultation on Incontinence Questionnaire short form (ICIQ-SF) at age 68 years.
The researchers found that UUI was reported by 12 percent of men and 19 percent of women at age 68 years. Independent risk factors for UUI included female sex, previous stroke or transient ischemic attack (TIA) diagnosis, increased body mass index (BMI), and hypertension (in men only) at age 60 to 64 years. The relative risk of more severe UUI symptoms was increased with female sex, increased BMI, and a previous diagnosis of stroke/TIA. The relationship between UUI and vascular risk factors in women was not affected by type and timing of menopause or hormone replacement therapy use.
"Multifactorial mechanisms lead to UUI, and vascular risk factors may contribute to the pathogenesis of bladder overactivity in addition to higher BMI," the authors write.
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Posted: March 2018