Skip to Content

Surgical Technique May Cut Positive Margin Rates in DCIS

WEDNESDAY, April 21, 2021 -- Cavity shave margin (CSM) resections may reduce positive margin rates in patients with pure ductal carcinoma in situ (DCIS), according to a study published in the April issue of the Journal of the American College of Surgeons.

Marissa Howard-McNatt, M.D., from Wake Forest University in Winston-Salem, North Carolina, and colleagues examined the impact of CSMs on margin status in patients with DCIS undergoing partial mastectomy. Following partial mastectomy performed per the surgeon's discretion, 109 patients were randomly assigned to CSM resection (58) or not.

The researchers found that 56.9 percent of the patients in the shave group had a positive margin before randomization, but only 20.7 percent had a positive margin after randomization to CSM compared with 33.3 percent with a positive margin in the no-shave group. CSM was associated with a significant reduction in the positive margin rate (odds ratio, 0.366) when controlling for size and grade of DCIS. Size of DCIS persisted as an independent predictor of positive margins (odds ratio, 1.646).

"Our study shows a significant reduction in positive margins," Howard-McNatt said in a statement. "This technique should be considered for DCIS patients."

Abstract/Full Text

© 2021 HealthDay. All rights reserved.

Read this next

Gender-Affirming Surgery Tied to Better Mental Health

WEDNESDAY, May 5, 2021 -- Gender-affirming surgery is associated with improved mental health outcomes among transgender and gender-diverse individuals, according to a study...

SLNB, RT Not Tied to Better Outcomes in Older Women With Breast Cancer

WEDNESDAY, May 5, 2021 -- For older patients with estrogen receptor (ER)-positive, clinically node-negative breast cancer, receipt of sentinel lymph node biopsy (SLNB) or adjuvant...

More Parity in Breast Reconstruction Seen With Medicaid Expansion

TUESDAY, May 4, 2021 -- Medicaid expansion was associated with increases in breast reconstruction rates among non-Hispanic Black (NHB) women, according to a study presented at the...

More News Resources

Subscribe to our Newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.