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Rotating Night Shift Work Tied to Increased Odds of T2DM

FRIDAY, Feb. 16, 2018 -- Rotating shift work which includes night shifts is associated with increased odds of type 2 diabetes, according to a study published online Feb. 12 in Diabetes Care.

CĂ©line Vetter, Ph.D., from the University of Colorado in Boulder, and colleagues examined associations of current and lifetime night shift work exposure (272,214 and 70,480 participants, respectively) with type 2 diabetes risk (6,770 and 1,191 prevalent cases, respectively).

The researchers found that all current night shift workers were at higher multivariable-adjusted odds for type 2 diabetes compared with day workers (odds ratios [OR], 1.15 [95 percent confidence interval (CI), 1.05 to 1.26], 1.18 [95 percent CI, 1.05 to 1.32], and 1.44 [95 percent CI, 1.19 to 1.73] for none or rare night shifts, some nights, and usual nights), except for current permanent night shift workers (odds ratio, 1.09 [95 percent CI, 0.93 to 1.27]). Working more night shifts per month correlated with increased odds of type 2 diabetes considering a person's lifetime work schedule and compared with never shift workers (<3/month: OR, 1.24 [95 percent CI, 0.90 to 1.68]; 3 to 8/month: OR, 1.11 [95 percent CI, 0.90 to 1.37]; and >8/month: OR, 1.36 [95 percent CI, 1.14 to 1.62]).

"Night shift work, especially rotating shift work including night shifts, is associated with higher type 2 diabetes odds and that the number of night shifts worked per month appears most relevant for type 2 diabetes odds," the authors write.

Two authors disclosed financial ties to the pharmaceutical and other industries.

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Posted: February 2018