Risk for Cancer Increased in Men, Women With T2DM
THURSDAY, May 9, 2019 -- Men and women with type 2 diabetes (T2D) have an increased risk for overall cancer and some site-specific cancers, according to a study published online May 9 in the Journal of Diabetes.
Jiying Qi, from the Shanghai Jiao Tong University School of Medicine, and colleagues examined the risk for 23 common types of cancer among patients with T2D. A total of 410,191 patients with T2D were identified from July 2013 to December 2016 based on the Shanghai Hospital Link database; the patients were followed until December 2017 for cancer incidence.
The researchers identified 8,485 cases of newly diagnosed cancer. Among men and women, the standardized incidence ratios (SIRs) for total cancer were 1.34 and 1.62, respectively. The risk for prostate cancer had the highest SIR (1.86) and cancers of the blood (leukemia and lymphoma), skin, thyroid, kidney, liver, pancreas, lung, colorectum, and stomach were also increased significantly among men with T2D. Significantly greater risks were seen for cancer of the nasopharynx (highest SIR, 2.33), liver, esophagus, thyroid, lung, pancreas, blood (lymphoma and leukemia), uterus, colorectum, breast, cervix, and stomach for women with T2D. The risk for gallbladder cancer was significantly reduced for women with T2D.
"These findings have the crucial implication that establishing strategies for cancer-specific regular screening and prevention care among patients with T2D are necessary in clinical practice," the authors write.
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Posted: May 2019
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