Skip to Content

Review: Aerobic Exercise Improves Hemodialysis-Related Symptoms

FRIDAY, March 26, 2021 -- Aerobic exercise improves several hemodialysis-related symptoms for adults on maintenance hemodialysis, according to a review published online March 25 in the Clinical Journal of the American Society of Nephrology.

Nicholas Hargrove, from the Max Rady College of Medicine at the University of Manitoba in Winnipeg, Canada, and colleagues conducted a systematic review to examine the effect of aerobic exercise on hemodialysis-related symptoms in adults with kidney failure undergoing maintenance hemodialysis. A total of 15 randomized controlled trials met the eligibility criteria.

For most symptoms, heterogeneous interventions and outcomes and a moderate-to-high risk for bias precluded meta-analysis. The researchers found that improvement in symptoms of restless legs syndrome, muscle cramping, and fatigue was seen with aerobic exercise compared with nonexercise controls. In a meta-analysis of depressive symptoms in studies using the Beck Depression Inventory, a greater reduction in the Beck Depression Inventory score was seen with exercise versus control (mean difference, −7.57).

"The review by Hargrove et al provides encouraging preliminary data to suggest aerobic exercise has the potential to alleviate many of the most bothersome symptoms," write the authors of an accompanying editorial. "Support for large, multicenter studies to confirm the benefits of exercise and determine which exercise approaches are most beneficial and most accessible and acceptable to patients is urgently needed. It will also be crucial to focus on development of infrastructure for the delivery of effective exercise interventions."

Several authors disclosed financial ties to the biopharmaceutical and medical device industries.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

© 2021 HealthDay. All rights reserved.

Read this next

Dialysis Patients Develop Lower Antibody Response to Pfizer COVID-19 Vaccine

MONDAY, April 12, 2021 -- Most patients with kidney failure undergoing regular dialysis develop a substantial antibody response after receiving the Pfizer-BioNTech COVID-19...

Mortality Risk Up for Dialysis Patients in March to July 2020

FRIDAY, April 9, 2021 -- Patients undergoing dialysis and those with kidney transplants had increased mortality risk in 2020 compared with 2017 to 2019, according to a study...

COVID-19 Case Fatality Rate High in Long-Term Dialysis Patients

TUESDAY, Feb. 16, 2021 -- Patients undergoing long-term dialysis who become infected with SARS-CoV-2 have a high COVID-19 case fatality rate, according to a study published online...

More News Resources

Subscribe to our Newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of in your inbox.