Skip to Content

High Refined Grain Intake Ups Risk for Mortality, Major CVD Events

THURSDAY, Feb. 4, 2021 -- A high intake of refined grains is associated with an increased risk for mortality and major cardiovascular disease events, according to a study published online Feb. 3 in The BMJ.

Sumathi Saminathan, Ph.D., from St. John's Research Institute in Bangalore, India, and colleagues conducted a prospective cohort study in 21 countries involving 148,858 participants with a median follow-up of 9.5 years. Intakes of refined grains, whole grains, and white rice were examined, and the association with mortality, major cardiovascular disease events, and their composite was estimated. Analyses were based on data from 137,130 participants without baseline cardiovascular disease.

The researchers found that 9.2 percent of participants had a composite outcome event during follow-up. Compared with the lowest category of intake (<50 g/day), the highest category of intake of refined grains (≥350 g/day or about seven servings) was associated with an elevated risk for total mortality, major cardiovascular disease events, and their composite (hazard ratios, 1.27, 1.33, and 1.28, respectively). There were associations seen for higher intakes of refined grains with higher systolic blood pressure. Intakes of whole grains or white rice were not significantly associated with health outcomes.

"Intakes of a combination of cereal grains with a lower intake of refined wheat products should be encouraged while promoting a higher intake of whole grains," the authors write. "Reduction in quantity and improvement in quality of carbohydrate is essential for better health outcomes."

Several authors disclosed financial ties to the pharmaceutical industry.

Abstract/Full Text

© 2021 HealthDay. All rights reserved.

Read this next

Hypertensive Disorders of Pregnancy Tied to Heart Damage 10 Years Later

FRIDAY, March 5, 2021 -- Women with a history of hypertensive disorders of pregnancy (HDP) and current hypertension show left ventricular remodeling a decade after delivery,...

CVD Risk Factors Tied to Cognitive Impairment in Schizophrenia

THURSDAY, March 4, 2021 -- Cardiovascular risk factors are associated with cognitive impairment among individuals with schizophrenia, according to a review and meta-analysis...

CV Risk Factors, Atherosclerosis May Alter Brain Metabolism

THURSDAY, March 4, 2021 -- Cardiovascular risk is associated with brain hypometabolism in asymptomatic middle-aged individuals with evidence of subclinical atherosclerosis,...

More News Resources

Subscribe to our Newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of in your inbox.