Probiotics Tied to Lower Preterm Delivery, Preeclampsia Risk
WEDNESDAY, Jan. 24, 2018 -- Probiotic milk consumption during pregnancy may be tied to a reduced incidence of preeclampsia and preterm delivery, according to a study published online Jan. 23 in BMJ Open.
Mahsa Nordqvist, M.D., from Sahlgrenska University Hospital in Sweden, and colleagues assessed whether probiotic milk intake before pregnancy, during early pregnancy, or during late pregnancy influences associations with preeclampsia and preterm delivery. The authors analyzed data from 70,149 singleton pregnancies resulting in live-born babies from the Norwegian Mother and Child Cohort Study. In the preeclampsia analysis, they included 37,050 nulliparous women, and in the preterm delivery analysis, they included 34,458 cases, with both iatrogenic and spontaneous preterm delivery with spontaneous term controls.
The researchers found that probiotic milk intake in late pregnancy, but not before or in early pregnancy, was significantly associated with lower preeclampsia risk (adjusted odds ratio, 0.8). On the other hand, a lower risk of preterm delivery was significantly associated with probiotic intake during early pregnancy but not before or during late pregnancy (adjusted odds ratio, 0.79).
"If future randomized controlled trials could establish a causal association between probiotics consumption and reduced risk of preeclampsia and preterm delivery, recommending probiotics would be a promising public health measure to reduce these adverse pregnancy outcomes," the authors write.
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Posted: January 2018