Primary PCI Use Down for Cancer Patients With STEMI
WEDNESDAY, Feb. 17, 2021 -- Patients with active cancer who have ST-elevation myocardial infarction (STEMI) receive primary percutaneous coronary intervention (pPCI) less often, but they have significantly lower rates of in-hospital all-cause mortality and major adverse cardiovascular and cerebrovascular events with pPCI, according to a study published online Feb. 3 in the European Heart Journal: Acute Cardiovascular Care.
Mohamed O. Mohamed, M.B.B.Ch., from Keele University in the United Kingdom, and colleagues retrospectively analyzed all STEMI hospitalizations between 2004 and 2015 from the National Inpatient Sample to examine the use and effectiveness of pPCI in patients with active cancer presenting with STEMI. Data were included for 1,870,815 patients with STEMI, of whom 2.1 percent had a current cancer diagnosis.
The researchers found that compared with those without cancer, patients with cancer received pPCI less often (from 54.2 percent for lung cancer to 70.6 percent for hematological cancer compared with 82.3 percent among those without cancer). Compared with the noncancer group, in the cancer groups, performance of pPCI was strongly associated with lower adjusted probabilities of major adverse cardiovascular and cerebrovascular events and all-cause mortality. No significant difference was seen in the estimated average pPCI treatment effect between the cancer and noncancer groups.
"The results indicate that heart attack patients should receive primary PCI regardless of whether or not they have cancer," Mohamed said in a statement. "Some patients with cancer are at elevated risk of bleeding and it was reassuring that the intervention did not result in an increased risk of bleeding events."
Several authors disclosed financial ties to the biotechnology and pharmaceutical industries.
© 2021 HealthDay. All rights reserved.
Posted: February 2021
Read this next
TUESDAY, March 2, 2021 -- A moderate-to-high level of past physical activity (PA) is associated with a lower risk for instant and 28-day death in relation to myocardial infarction...
MONDAY, March 1, 2021 -- In a clinical guideline from the American Society of Hematology, published online Feb. 11 in Blood Advances, recommendations are presented for the...
FRIDAY, Feb. 26, 2021 -- From 2008 to 2017, the rates of recurrent myocardial infarction (MI), recurrent coronary heart disease (CHD) events, heart failure hospitalization, and...
More News Resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our Newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.