Skip to Content

Overall Pregnancy, Live Birth Outcomes Unchanged in Psoriasis

WEDNESDAY, Feb. 17, 2021 -- Overall pregnancy and live birth outcomes are similar for women with psoriasis and for the general population, according to a study published online Feb. 3 in JAMA Dermatology.

Alexa B. Kimball, M.D., M.P.H., from the Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, and colleagues reported pregnancy outcomes observed in the Psoriasis Longitudinal Assessment and Registry (PSOLAR). Data were included for 2,224 women of childbearing age (18 to 45 years).

The researchers identified 298 pregnancies among 220 women, with a general fertility rate of 18.9 per 1,000 women aged 18 to 45 years. Overall, 81.9 percent of the pregnancies resulted in birth, and 13.8 and 4.4 percent ended in spontaneous abortion and were electively terminated, respectively. Gestational age was available for 243 births: 90.9 percent were full term and 9.1 percent were born prematurely. Overall, there were 231 healthy newborns and 10, two, and one infants with a neonatal problem, a congenital anomaly, and stillbirth, respectively. Two hundred fifty-two of the 298 pregnancies were associated with biologic exposure before or during pregnancy. Women exposed to biologics had similar pregnancy outcomes as those exposed to nonbiologics. Of the women who became pregnant, at the time of enrollment into the registry, 33.8 percent had obesity and 55.0 percent were past or current smokers.

"Pregnancy outcomes among women with moderate-to-severe psoriasis in PSOLAR have remained consistent with previously reported data and the general population," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.

Abstract/Full Text

© 2021 HealthDay. All rights reserved.

Posted: February 2021

Read this next

Treatment to Lower RA Disease Activity Feasible in Pregnancy

THURSDAY, Feb. 25, 2021 -- Low disease activity and remission are feasible goals for women with rheumatoid arthritis (RA) cared for with a modern treatment approach during...

More Than Half of U.S. Adults Use Dietary Supplements

THURSDAY, Feb. 25, 2021 -- During 2017 to 2018, 57.6 percent of U.S. adults used any dietary supplement in the previous 30 days, according to a February data brief published by...

Children Conceived by ART Are Shorter, Lighter at Birth

TUESDAY, Feb. 23, 2021 -- Children conceived by assisted reproduction technology (ART) are shorter and lighter at birth than those conceived naturally, but have similar height and...

More News Resources

Subscribe to our Newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.