Skip to Content

Mortality Up With Surgery Within Six Weeks of SARS-CoV-2 Infection

MONDAY, March 15, 2021 -- Mortality is increased for patients undergoing surgery within six weeks of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to a study published online March 9 in Anesthesia.

Dmitri Nepogodiev, M.B.Ch.B., from the University of Birmingham in the United Kingdom, and colleagues examined the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection in an international, multicenter study. Data were included for patients undergoing elective or emergency surgery during October 2020.

The researchers found that 3,127 of the 140,231 patients (2.2 percent) from 116 countries had a preoperative SARS-CoV-2 diagnosis. In patients without SARS-CoV-2, adjusted 30-day mortality was 1.5 percent. For those with a preoperative SARS-CoV-2 diagnosis, patients having surgery within zero to two, three to four, and five to six weeks of diagnosis had increased mortality (4.1, 3.9 and 3.6 percent, respectively; odds ratios [95 percent confidence intervals], 3.22 [2.55 to 4.07], 3.03 [2.03 to 4.52], and 2.78 [1.64 to 4.71]). Mortality was similar to baseline for surgery performed at least seven weeks after SARS-CoV-2 diagnosis (1.5 percent; odds ratio, 1.02 [0.66 to 1.56]). After at least a seven-week delay in undertaking surgery following SARS-CoV-2 infection, mortality was higher for those with ongoing symptoms compared with those whose symptoms had resolved or who had been asymptomatic (6.0 percent versus 2.4 and 1.3 percent, respectively).

"We found that risks of postoperative morbidity and mortality are greatest if patients are operated within six weeks of diagnosis of SARS-CoV-2 infection," the authors write.

Abstract/Full Text

© 2021 HealthDay. All rights reserved.

Read this next

FDA: Multiple Violations Found at Baltimore Plant Making COVID-19 Vaccines

WEDNESDAY, April 21, 2021 -- Improper disinfection and not following contamination prevention protocols are among the nine violations found by U.S. Food and Drug Administration...

Supply May Soon Outstrip Demand in U.S. COVID-19 Vaccine Rollout

WEDNESDAY, April 21, 2021 -- Since the first COVID-19 vaccine was approved in December, millions of Americans have eagerly sought to find and receive one. But a new report reveals...

Globally, No Increase Seen in Suicides in Early COVID-19 Pandemic

WEDNESDAY, April 21, 2021 -- In high-income and upper-middle-income countries, suicide numbers remained unchanged or declined in the early months of the pandemic versus the...

More News Resources

Subscribe to our Newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of in your inbox.