Mortality, Preeclampsia Up for Women With COVID-19 Giving Birth
WEDNESDAY, Jan. 20, 2021 -- Among U.S. women hospitalized for childbirth, the rates of death and certain adverse events are increased among those diagnosed with COVID-19, according to a research letter published online Jan. 15 in JAMA Internal Medicine.
Karola S. Jering, M.D., from Brigham and Women's Hospital in Boston, and colleagues compared clinical characteristics and outcomes of women, with and without COVID-19, who gave birth in the hospital between April 11 and Nov. 23, 2020. Data were included for 406,446 women hospitalized for childbirth; 1.6 percent had COVID-19.
The researchers found that pregnant women with COVID-19 were younger and more often Black and/or Hispanic with diabetes and obesity compared to pregnant women without COVID-19. Of the 6,380 women with COVID-19 who gave birth, 98.9 percent were discharged to home and 3.3, 1.3, and 0.1 percent needed intensive care, mechanical ventilation, and died in the hospital, respectively. In-hospital mortality was significantly higher in women with versus without COVID-19 (141 versus 5.0 deaths per 100,000 women). Women with versus without COVID-19 had higher rates of myocardial infarction (0.1 versus 0.004 percent) and venous thromboembolism (0.2 versus 0.1 percent). The odds of preeclampsia and preterm birth were increased in association with COVID-19 (adjusted odds ratios [95 percent confidence intervals], 1.21 [1.11 to 1.33] and 1.17 [1.06 to 1.29], respectively), but stillbirth was not (adjusted odds ratio, 1.23; 95 percent confidence interval, 0.87 to 1.75).
"As studies investigating therapies for COVID-19 have largely excluded pregnant women, the data also underscore the importance of including this population in clinical trials of treatments and vaccine," the authors write.
Several authors disclosed financial ties to the biopharmaceutical industry.
© 2021 HealthDay. All rights reserved.
Posted: January 2021
Further Support and Information on COVID-19
Read this next
Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of Feb. 22 to 26, 2021. This roundup...
FRIDAY, Feb. 26, 2021 -- A centralized online portal to help Americans find nearby COVID-19 vaccination sites is being backed by the U.S. Centers for Disease Control and...
FRIDAY, Feb. 26, 2021 -- In a research letter published online Feb. 16 in Open Forum Infectious Diseases, cutaneous findings are described for multisystem inflammatory syndrome in...
More News Resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our Newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.