Skip to Content

Mediterranean Diet May Protect Against Memory Decline

FRIDAY, May 7, 2021 -- Following a Mediterranean-like diet (MeDi) may be protective against memory decline and mediotemporal atrophy, according to a study published online May 5 in Neurology.

Tommaso Ballarini, Ph.D., from the German Center for Neurodegenerative Diseases in Bonn, and colleagues analyzed cross-sectional data from the German Longitudinal Cognitive Impairment and Dementia Study involving 512 individuals: 169 cognitively normal, 53 Alzheimer disease (AD) relatives, 209 with subjective cognitive decline, and 81 with mild cognitive impairment. MeDi adherence was defined based on food frequency questionnaires. In 226 individuals, AD-related biomarkers (Aß42/40 ratio and pTau181) were assessed in cerebrospinal fluid.

The researchers found that higher adherence to MeDi was associated with larger mediotemporal gray matter volume, better memory, and less amyloid (Aß42/40 ratio) and pTau181 pathology. The association between MeDi and memory was partially mediated by mediotemporal volume (40 percent indirect mediation). The associations between Aß42/40 ratio, pTau181, and mediotemporal atrophy were favorably moderated by MeDi. After correcting for ApoE-ε4 status, the results were consistent.

"Our study suggests that eating a diet that's high in unsaturated fats, fish, fruits, and vegetables, and low in dairy and red meat may actually protect your brain from the protein build-up that can lead to memory loss and dementia," Ballarini said in a statement. "These results add to the body of evidence that show what you eat may influence your memory skills later on."

One author disclosed financial ties to the biopharmaceutical industry.

Abstract/Full Text (subscription or payment may be required)

© 2021 HealthDay. All rights reserved.

Read this next

Combining Low-Salt, DASH Diets May Reduce Cardiac Damage

THURSDAY, June 17, 2021 -- Dietary interventions, like the Dietary Approaches to Stop Hypertension (DASH) diet and low sodium consumption, can improve cardiovascular risk factors...

Plant-Centered Diet May Lower LDL Cholesterol, CVD Risk

TUESDAY, June 15, 2021 -- Dietary strategies aimed solely at lowering saturated fat intake may be less effective in reducing cardiovascular disease (CVD) than recommendations for...

Most U.S. Adults Do Not Eat Enough Dietary Fiber

MONDAY, June 14, 2021 -- Few U.S. adults regularly eat enough dietary fiber, according to a study presented during Nutrition 2021, the annual meeting of the American Society for...

More News Resources

Subscribe to our Newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of in your inbox.