Machine Learning Models Can Predict Gestational Diabetes
THURSDAY, Jan. 7, 2021 -- Machine learning (ML) models are highly accurate for predicting gestational diabetes mellitus (GDM) in early pregnancy in a Chinese population, according to a study published online Dec. 22 in the Journal of Clinical Endocrinology & Metabolism.
Yan-Ting Wu, Ph.D., from the Shanghai Jiao Tong University, and colleagues extracted data from 73 variables during the first trimester from electronic medical record systems. Seventeen variables were selected for early GDM prediction based on an ML-driven feature selection method; to facilitate clinical application, seven variables were selected. Using the seven- and 73-variable datasets, advanced ML approaches were used to build models to predict early GDM. The training and testing sets included 16,819 and 14,992 cases, respectively.
The researchers found that the deep neural network model achieved high discriminative power using 73 variables, with an area under the curve (AUC) of 0.80. Effective discriminative power was also achieved with the seven-variable logistic regression model (AUC, 0.77). Compared with a body mass index (BMI) of 17 to 18 kg/m², low BMI (≤17 kg/m²) was related to an increased risk for GDM. For predicting GDM, total triiodothyronine and total tetraiodothyronine were superior to free triiodothyronine and free tetraiodothyronine. A promising predictive value was also seen for lipoprotein(a) (AUC, 0.66).
"These findings can help clinicians identify women at high risk of diabetes in early pregnancy and start interventions such as diet changes sooner," a coauthor said in a statement.
© 2021 HealthDay. All rights reserved.
Posted: January 2021
Read this next
THURSDAY, Jan. 14, 2021 -- Exercise during the first trimester of pregnancy reduces the risks for abnormal glucose screening and gestational diabetes mellitus (GDM), according to...
WEDNESDAY, Jan. 13, 2021 -- Women with pregnancy after versus before a multiple sclerosis (MS) diagnosis have fewer children and at an older age, according to a study published in...
WEDNESDAY, Jan. 13, 2021 -- Use of a higher hemoglobin transfusion threshold does not lower the risk for death or neurodevelopmental impairment at 22 to 26 months of age among...
More News Resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our Newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.