Lymphoma Survivors at Risk for Developing Chronic Kidney Disease
Sanjal H. Desai, M.D., from the Medstar Washington Hospital Center in Washington, D.C., and colleagues describe patterns of long-term CKD in lymphoma survivors. At diagnosis and years 1, 2, 5, and 10, glomerular filtration rate (GFR) was recorded.
The researchers found that among 397 patients (median age, 55.3 years; 54 percent male; 60 percent African-American), 42 percent had hypertension, 15 percent had diabetes mellitus, 13 percent had hyperuricemia, 86 percent received chemotherapy, and 14 percent had baseline CKD. Just under one-third of patients (31 percent) developed CKD within 10 years of lymphoma diagnosis. There was a significant increase noted in the probability of CKD development with time (23 percent at year 1 increased to 41 percent at year 10). The investigators observed a decline in GFR of 4.6 mL/min/per year. CKD was predicted by age, hypertension, hyperuricemia, and diabetes (in young patients).
"These findings underscore the need to monitor renal function in long-term lymphoma survivors and lay foundation for future prospective studies to define strategies to prevent CKD in lymphoma survivors," the authors write.
© 2020 HealthDay. All rights reserved.
Posted: July 2020
Read this next
THURSDAY, Sept. 24, 2020 -- Acute kidney injury (AKI) in hospitalized patients with COVID-19 is associated with a significantly higher risk for in-hospital death, according to a...
FRIDAY, Sept. 11, 2020 -- Reducing urinary protein aids patients with the rare kidney disease focal segmental glomerulosclerosis (FSGS), according to a study published online Aug....
THURSDAY, Sept. 3, 2020 -- Adults who experience more episodes of moderate/high end-stage renal disease (ESRD) risk have worse performance in cognitive domains in middle age,...
More News Resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
- Monthly Update Archive
Subscribe to our Newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.