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Long-Term Diastolic Dysfunction Seen After Early Preeclampsia

TUESDAY, July 23, 2019 -- Women with a history of early or preterm preeclampsia have an increased prevalence of diastolic dysfunction, according to a review published online July 2 in the Australasian Journal of Ultrasound in Medicine.

Archana S. Thayaparan, M.B.Ch.B., from Western Health in St Albans, Australia, and colleagues conducted a systematic review to identify studies assessing cardiac function 12 weeks postpartum in women with a history of preeclampsia.

The researchers identified 13 studies that measured cardiac function by transthoracic echocardiography between six months and 18 years following a pregnancy complicated by preeclampsia. Across studies, there were common findings of increased diastolic dysfunction, increased left ventricular mass index, and concentric hypertrophy in women with a history of preeclampsia, compared to women with uncomplicated pregnancy histories. Findings were primarily seen in women with a history of early or preterm preeclampsia.

"The use of echocardiography could detect cardiac dysfunction in the asymptomatic stage and guide more intensive risk factor modification in these women," the authors write.

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Posted: July 2019