Inverse Link for Mediterranean Diet Score, Severe Psoriasis
WEDNESDAY, Aug. 8, 2018 -- Patients with severe psoriasis have low levels of adherence to the Mediterranean diet (MEDI-LITE), according to a study published online July 25 in JAMA Dermatology.
Céline Phan, M.D., from Mondor Hospital in France, and colleagues examined the correlation between a score reflecting adhesion to MEDI-LITE and the onset and/or severity of psoriasis in the NutriNet-Santé program. Patients with psoriasis were identified via validated online self-completed questionnaire and were classified according to disease severity. During the first two years of participation in the cohort, data on dietary intake were gathered to calculate the MEDI-LITE score.
The researchers found that 23 percent of the 158,361 NutriNet Santé participants responded to the psoriasis questionnaire. Overall, 3,557 individuals (10 percent) reported having psoriasis. In 24.7 percent of cases, the condition was severe, and incident cases were recorded in 8.4 percent. There was a significant inverse correlation between MEDI-LITE score and having severe psoriasis (odds ratio, 0.71 for the MEDI-LITE score's second tertile [95 percent confidence interval, 0.55 to 0.92] and odds ratio, 0.78 for the third tertile [95 percent confidence interval, 0.59 to 1.01]) after adjustment for confounding variables.
"If these findings are confirmed, adherence to a Mediterranean diet should be integrated into the routine management of moderate to severe psoriasis," the authors write.
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Posted: August 2018