Heart Risks Tied to Transwomen's Hormone Therapy
TUESDAY, July 10, 2018 -- Transwomen who undergo hormone therapy may face higher chances of blood clots, stroke and heart attack, a new study suggests.
The term transwoman refers to a woman who is designated male at birth. Some undergo hormone therapy to minimize their male characteristics and maximize female traits.
"While our study confirmed elevated risks of certain vascular events related to hormone therapy, these risks need to be weighed against the important benefits of treatment," Dr. Michael Goodman, a professor of epidemiology at Emory University in Atlanta, said in a school news release.
The researchers compared nearly 4,700 transgender and gender non-conforming people with more than 97,000 men and women whose gender identity matches their assigned sex at birth. The term for this is cisgender.
Blood clots in the veins (venous thromboembolism) were nearly two times higher in transwomen. Rates of stroke and heart attack among transwomen were 80 to 90 percent higher than those in women without gender issues, but similar to the rates in cisgender men.
The higher rates of blood clots and stroke among transwomen were more noticeable several years after they began estrogen therapy, according to the study, which did not prove a cause-and-effect link.
Further research is needed to learn more about how specific hormone formulations, doses, drug combinations and types of administration may affect heart risks in transwomen, the study authors noted.
The findings were published July 9 in Annals of Internal Medicine.
© 2020 HealthDay. All rights reserved.
Posted: July 2018
Read this next
WEDNESDAY, Sept. 16, 2020 -- Most people now know that COVID-19 can cause blood clots, potentially leading to paralysis, stroke, heart attack and death. While it's not clear...
MONDAY, Aug. 17, 2020 (American Heart Association News) -- After nearly a decade of steady decline, the death rate for people with blood clots in the lungs reversed course and...
FRIDAY, July 31, 2020 -- For Ron Panzok and many patients like him, the battle with COVID-19 didn't end when he left the hospital. From the ambulance ride to North Shore...
More News Resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
- Monthly Update Archive
Subscribe to our Newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.