Skip to Content

Head Injury Linked to Long-Term Risk for Dementia

FRIDAY, March 19, 2021 -- Head injury is associated with dementia over a median 25 years of follow-up, according to a study published online March 9 in Alzheimer's & Dementia.

Andrea L.C. Schneider, M.D., Ph.D., from the University of Pennsylvania Perelman School of Medicine in Philadelphia, and colleagues conducted a prospective cohort study involving 14,376 participants enrolled in the Atherosclerosis Risk in Communities study to examine the associations of head injury with dementia during a median 25 years of follow-up.

The researchers found that head injury correlated with dementia risk (hazard ratio, 1.44), with evidence of a dose-response pattern (one head injury: hazard ratio, 1.25; two or more head injuries: hazard ratio, 2.14). The association was stronger among female versus male participants (hazard ratios, 1.69 versus 1.15) and for White versus Black participants (hazard ratios, 1.55 versus 1.22).

"Our findings show that the number of head injuries matter -- more head injuries are associated with greater risk for dementia," Schneider said in a statement. "The dose-dependence of this association suggests that prevention of head injury could mitigate some risk of dementia later in life. While head injury is not the only risk factor for dementia, it is one risk factor for dementia that is modifiable by behavior changes such as wearing helmets and seat belts."

Abstract/Full Text (subscription or payment may be required)

© 2021 HealthDay. All rights reserved.

Read this next

Cognitive Deficits in Childhood Tied to Later Mental Health Disorders

WEDNESDAY, April 21, 2021 -- Specific cognitive deficits in childhood are distinctively associated with different mental health disorders, like borderline personality disorder,...

Traumatic Brain Injury Ups Risk for Future Stroke

WEDNESDAY, April 21, 2021 -- Traumatic brain injury (TBI) is an independent risk factor for stroke, according to a review published online April 4 in the International Journal of...

Neighborhood Disadvantage Tied to Cognitive Decline in Older Adults

THURSDAY, April 15, 2021 -- There is a longitudinal association of neighborhood-level disadvantage with cortical thinning and cognitive decline, according to a study published...

More News Resources

Subscribe to our Newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of in your inbox.