Greater Levels of Exercise May Protect Brain in Later Life
THURSDAY, Jan. 14, 2021 -- Greater levels of moderate- to vigorous-intensity physical activity (MVPA) in midlife may protect against cerebrovascular sequelae in later life, according to a study published online Jan. 6 in Neurology.
Priya Palta, Ph.D., from the Columbia University Irving Medical Center in New York City, and colleagues used data from 1,604 participants in the Atherosclerosis Risk in Communities Study to examine the impact of leisure-time MVPA on the brain in midlife or late life. Magnetic resonance imaging in late life was used to quantify the presence of cerebrovascular lesions, white matter hyperintensities, white matter integrity (mean fractional anisotropy [FA] and mean diffusivity [MD]), and grey matter volumes.
Of the participants, 34, 11, 16, and 39 percent reported no, low, middle, and high MVPA in midlife, respectively. The researchers found that high MVPA compared with no MVPA in midlife correlated with more intact white matter integrity in late life (mean FA difference, 0.13 per standard deviation; mean MD difference, −0.11 per standard deviation). There was also a correlation seen for high MVPA in midlife with lower odds of lacunar infarcts (odds ratio, 0.68). No correlation was seen for high MVPA with grey matter volumes. Compared with no MVPA in late life, high MVPA was associated with most brain measures.
"Our results show that staying active during mid-life may have real brain benefits," Palta said in a statement. "In particular, consistently high levels of mid-life MVPA were associated with fewer brain lesions in later life."
One author disclosed financial ties to the pharmaceutical industry.
© 2021 HealthDay. All rights reserved.
Posted: January 2021
Read this next
WEDNESDAY, Jan. 27, 2021 -- Exercise-based cardiac rehabilitation (CR) can improve cardiovascular endurance and health status among stroke survivors, according to a study...
WEDNESDAY, Jan. 27, 2021 -- Heart disease remains the leading cause of death worldwide, with 18.6 million deaths attributed to cardiovascular disease (CVD) globally in 2019,...
MONDAY, Jan. 25, 2021 -- For patients with atrial fibrillation (AF), low-to-moderate alcohol intake is not associated with an increased risk for stroke or other cardiovascular...
More News Resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our Newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.