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Genedata Expands Collaboration with HepatoSys Systems Biology Network

BASEL, Switzerland – On February 9, 2007, Swiss-based computational biology provider Genedata AG announced a three-year expansion of their collaboration with the HepatoSys research network. HepatoSys, an interdisciplinary initiative funded in 2003 by leading German research centers, aims to understand the physiology and pathophysiology of the human liver cell using a systems biology approach.

In the first funding period of HepatoSys, Genedata had been tasked to develop and establish a computational platform serving as the consortium’s central data storage and analysis infrastructure. The platform - built on Genedata’s established products Phylosopher® and Expressionist® - was successfully deployed and is now being used by the consortium. The centralized data storage infrastructure enables an integrative approach to the interpretation of systems biology modeling results in the context of experimental findings, including high-throughput transcriptomics, proteomics and metabolomics data.

Taking the collaboration to the next level, Genedata will now work on data analysis projects to interpret the huge amounts of molecular profiling data generated within the HepatoSys consortium.“After having built successfully on Genedata’s track record in developing our scientific computing infrastructure, we see a tremendous opportunity in bringing together our academic expertise with Genedata’s know-how to transfer systems biology applications to the pharmaceutical industry,” said Prof. Jens Timmer, scientific spokesman for HepatoSys.

“The ambitous goal to simulate complex biochemical networks and their regulation in liver cells is highly relevant for innovative biomedical applications,” explained Prof. Irmgard Merfort, Institute for Pharmaceutical Sciences, University of Freiburg. “Cellular processes such as programmed cell death and regeneration of liver cells are of great scientific and medical interest. Genedata will help us to identify new biomarkers for disease diagnostics and to pave the way for novel therapeutic approaches in tissue regeneration, cancer and inflammation.”

Dr. Othmar Pfannes, CEO of Genedata, adds: “Genedata’s contributions to concrete scientific projects show that we are considered to be a valuable partner, not only on the technical, but also on the scientific side. HepatoSys is yet another long-term relationship that proves Genedata’s commitment to innovative systems biology applications”.

Contact Genedata

Dr. Tobe Freeman
Manager Public Relations
Phone +41 61 697 8510
Fax +41 61 697 7244

Contact HepatoSys

Dr. Ute Heisner
Project Management
Phone +49 761 203 5803
Fax +49 761 203 5967

About Genedata Genedata specializes in discovery informatics for biotech, pharmaceuticals and the life sciences. The company offers expertise in research informatics combined with open and scalable computational solutions, including Genedata Phylosopher® for integrating, structuring, analyzing research data, Genedata Screener® for high throughput screening analysis, and Genedata Expressionist® for drug safety studies and toxico-genomics applications. Founded in 1997 as a privately held spin-off from Novartis, Genedata is headquartered in Basel, Switzerland and has branches in Munich (Germany), Boston and San Francisco (USA), and Tokio (Japan).
For more information about Genedata, please visit:

About HepatoSys HepatoSys is a competence network of more than 40 research groups from academia, industry, and clinics in Germany. The groups are funded by the Federal Ministry of Education and Research (BMBF) to support interdisciplinary research, to establish methods and tools, and to develop data-based models of physiological processes in hepatic cell model systems. For more information about HepatoSys, please visit: .

Disclaimer The statements in this press release that relate to future plans, events or performance are forward-looking statements that involve risks and uncertainties, including risks associated with uncertainties related to contract cancellations, developing risks, competitive factors, uncertainties pertaining to customer orders, demand for products and services, development of markets for the Company's products and services. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. The Company undertakes no obligation to release publicly the result of any revisions to these forward-looking statements that may be made to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events.

Posted: February 2007