Exposure to Secondhand Smoke May Raise Risk for Oral Cancer
WEDNESDAY, April 28, 2021 -- There seems to be a causal association between secondhand smoke (SHS) exposure and oral cancer, according to a systematic review and meta-analysis published online April 26 in Tobacco Control.
Lorena C. Mariano, from the Instituto Universitário de Ciências da Saúde in Gandra, Portugal, and colleagues conducted a systematic review and meta-analysis to examine studies reporting the associations of SHS and the risk for oral cancer. Data were included for five studies, with a total of 1,179 cases and 5,798 controls and 3,452 individuals exposed and 3,525 not exposed to SHS.
The researchers found that the overall odds ratio for oral cancer was 1.51 (95 percent confidence interval, 1.20 to 1.91; P = 0.0004), without significant heterogeneity (I2= 0 percent; P = 0.41). Compared with nonexposed individuals, the risk for oral cancer was increased with duration of exposure of more than 10 to 15 years (odds ratio, 2.07; 95 percent confidence interval, 1.54 to 2.79; P < 0.00001), with no significant heterogeneity (I2= 0 percent; P = 0.76).
"Our systematic review and meta-analysis support a consistent and statistically significant association between SHS exposure and the risk of oral cancer," the authors write. "Moreover, the analyses of exposure response, including by duration of exposure (more than 10 or 15 years) to SHS, further supports causal inference."
© 2021 HealthDay. All rights reserved.
Posted: April 2021
Read this next
FRIDAY, May 14, 2021 -- Young Black women show a high prevalence of cardiovascular risk factors, according to a study presented at the annual meeting of the American College of...
FRIDAY, May 7, 2021 -- Dual use of an electronic nicotine delivery system (ENDS) and smoked tobacco is associated with an increased risk for incident respiratory symptoms compared...
THURSDAY, April 29, 2021 -- The U.S. Food and Drug Administration on Thursday proposed a ban on menthol cigarettes, a move that the agency has tried before and one that public...
More News Resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our Newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.