Disparities Seen in Pediatric Sepsis Outcomes in the U.S.
WEDNESDAY, Dec. 23, 2020 -- For children with severe sepsis, outcomes vary by race or ethnicity and by insurance status, according to a study published online Dec. 14 in The Lancet Child & Adolescent Health.
Hannah K. Mitchell, B.M.B.S., from the Children's Hospital of Philadelphia, and colleagues conducted a retrospective cohort study using data from the 2016 Healthcare Cost and Utilization Project Kids' Inpatient Database. The association between race or ethnicity and insurance status and hospital mortality was examined among 12,297 children with severe sepsis who were admitted to 1,253 hospitals; the final cohort included 9,816 children.
The researchers found that compared with White children, Black children had higher odds of death (adjusted odds ratio, 1.19), driven by higher Black mortality in the Southern and Western United States (adjusted odds ratios, 1.30 and 1.58, respectively). There was evidence of longer hospital stays for Hispanic and Black children (adjusted hazard ratios, 0.94 and 0.88, respectively), especially Black neonates (adjusted hazard ratio, 0.53). There was no difference in survival noted for publicly and privately insured children; increased mortality was seen in association with "other" insurance status (self-pay, no charge, and other: adjusted odds ratio, 1.30).
"Future research should look for further disparities in sepsis care and outcomes, as well as explore the mechanisms that underlie their existence," the authors write. "A clearer understanding of the reasons that these disparities exist will enable health care systems to develop interventions to combat them."
© 2021 HealthDay. All rights reserved.
Posted: December 2020
Read this next
TUESDAY, Jan. 12, 2021 -- Improving hospital nurse staffing could significantly reduce deaths from sepsis, according to a study published online Dec. 9 in the American Journal of...
More News Resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our Newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.