Skip to Content

Contraceptives Beneficial for Premature Ovarian Insufficiency

THURSDAY, June 25, 2020 -- For women with premature ovarian insufficiency (POI), continuous use of combined oral contraceptives (COC) is associated with increased bone mineral density (BMD), similar to that seen with high-dose hormone therapy (HT), according to a study published online June 22 in Menopause.

Lívia B. Carvalho Gazarra, from the University of Campinas in Brazil, and colleagues conducted an observational study of women with POI to compare the use of COC to the use of low-dose HT, high-dose HT, tibolone, or no treatment. Every two years, bone density scans were performed. For the lumbar spine, total femur, and femoral neck, the difference between final and initial BMD values was calculated. Overall, 420 scans of 119 women were analyzed.

The researchers found that in the COC and high-dose HT groups, the BMD deltas at the lumbar spine and total femur were greater. The differences between the two scans at the lumbar spine were greater in the COC group than the low-dose HT, untreated, and tibolone groups (mean differences, −0.043, −0.056, and −0.050, respectively). Compared with COC, the low-dose HT group had lower total femur BMD decreases and delta (−0.038).

"The use of COC on a continuous schedule could be associated with improvement in bone mass, as reflected in the results of the present study in which there was an increase in bone mass at least similar to that found with the higher dose of HT," the authors write.

Abstract/Full Text (subscription or payment may be required)

© 2021 HealthDay. All rights reserved.

Read this next

Decline in Births Linked to COVID-19 Pandemic Societal Shutdown

FRIDAY, June 4, 2021 -- There was an initial decline in births in association with the COVID-19 pandemic societal lockdown, but a birth volume surge is anticipated in summer 2021...

CDC: Self-Administered Subcutaneous DMPA Should Be Made Available

FRIDAY, May 21, 2021 -- Self-administered subcutaneous depot medroxyprogesterone acetate (DMPA-SC) should be made available as an additional approach for contraception, according...

Women Physicians Delay Childbearing Versus Nonphysicians

TUESDAY, May 4, 2021 -- Compared with nonphysicians, women physicians delay childbearing, with median age at first childbearing of 32 and 27 years, respectively, according to a...

More News Resources

Subscribe to our Newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of in your inbox.