Cardiac CT Can Derive Thoracic Bone Mineral Density, Fracture Risk
WEDNESDAY, July 15, 2020 -- Cardiac computed tomography (CT) can identify individuals with low bone mineral density (BMD) and increased fracture risk, according to a study published online July 14 in Radiology.
Josephine Therkildsen, M.D., from the Hospital Unit West in Herning, Denmark, and colleagues examined the correlation between fracture rate and thoracic BMD derived from cardiac CT in a prospective cohort study. A total of 1,487 patients were referred for cardiac CT for evaluation of ischemic heart disease between September 2014 and March 2016 and were followed through June 30, 2018.
The researchers found that 12 percent of the patients had very low BMD. During follow-up, 5.3 percent of patients were diagnosed with an incident fracture; the fracture was osteoporosis-related in 31 of these 80 patients. Very low BMD was associated with an increased rate of any fracture and any osteoporosis-related fracture (hazard ratio, 2.6 and 8.1, respectively) compared with normal BMD in unadjusted analyses. Very low BMD remained associated with any fracture and any osteoporosis-related fracture after adjustment for age and sex (hazard ratios, 2.1 and 4.0, respectively).
"Our results represent a step toward appraisal and recognition of the clinical utility of opportunistic BMD screening from cardiac CT," the authors write.
Several authors disclosed financial ties to the biopharmaceutical and medical device industries.
© 2020 HealthDay. All rights reserved.
Posted: July 2020
More News Resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
- Monthly Update Archive
Subscribe to our Newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.