Skip to Content

Botox Injections May Ease Depression

MONDAY, Aug. 3, 2020 -- Botox injections, which are commonly used to lessen wrinkles, migraines, muscle spasms, excessive sweating, and incontinence, may also help treat depression, according to a study published online July 30 in Scientific Reports.

Tigran Makunts, Pharm.D., from the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California in San Diego and the U.S. Food and Drug Administration, and colleagues used the FDA Adverse Event Reporting System database to look for statistically significant differences between nearly 40,000 people who experienced an adverse event after being treated with Botox for a variety of reasons and patients who received different treatments for the same reasons. The authors measured how absent depression was within the reports of those who received Botox and compared it to how absent depression was in the control group.

The researchers found that patients treated with Botox for six different conditions and in six injection sites reported depression 40 to 88 percent less often than those who received other treatments for the same conditions. Clinicians have observed that Botox injections in the forehead may treat depression, and clinical trials are currently testing this theory, but this study revealed that the association existed when Botox was injected in six different sites, not just the forehead.

"This finding is exciting because it supports a new treatment to affect mood and fight depression, one of the common and dangerous mental illnesses -- and it's based on a very large body of statistical data, rather than limited-scale observations," Makunts said in a statement.

One author disclosed financial ties to Allergan, the maker of Botox, which was acquired by AbbVie in 2019.

Abstract/Full Text

© 2021 HealthDay. All rights reserved.

Read this next

Cannabis Use Linked to Suicidality in Young Adults

WEDNESDAY, June 23, 2021 -- The adjusted prevalence of suicidal ideation, plan, and attempt in young U.S. adults increased from 2008-2009 to 2018-2019 after controlling for major...

Suicide Deaths by Firearms Up Significantly in Young People

WEDNESDAY, June 23, 2021 -- Deaths from suicide, particularly by firearms, are dramatically increasing among young people, according to a study published online May 31 in the...

Paternal Depression May Linger After Child Discharged From NICU

FRIDAY, June 18, 2021 -- Parents with a baby in the neonatal intensive care unit (NICU) are at risk for depression, with fathers not seeing the same improvement in symptoms...

More News Resources

Subscribe to our Newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of in your inbox.