Skip to Content

Benefit of E-Cigarettes for Quitting Smoking Unclear

THURSDAY, Nov. 12, 2020 -- It is unclear whether the addition of nicotine electronic cigarettes to counseling leads to higher rates of smoking cessation than counseling alone among adults motivated to quit, according to the results of a study published in the Nov. 10 issue of the Journal of the American Medical Association.

Mark J. Eisenberg, M.D., from McGill University in Montreal, and colleagues randomly assigned adults motivated to quit smoking from November 2016 to September 2019 at 17 Canadian sites to nicotine e-cigarettes (128 participants), non-nicotine e-cigarettes (127 participants), or no e-cigarettes (121 participants) for 12 weeks, with all receiving individual counseling. Self-reported smoking status was assessed at 12 and 24 weeks.

The researchers found that the point prevalence of abstinence was significantly greater for nicotine e-cigarettes plus counseling versus counseling alone at 12 weeks (21.9 versus 9.1 percent; risk difference [RD], 12.8; 95 percent confidence interval [CI], 4.0 to 21.6), but not 24 weeks (17.2 versus 9.9 percent; RD, 7.3; 95 percent CI, –1.2 to 15.7). For non-nicotine e-cigarettes plus counseling versus counseling alone, the point prevalence for abstinence was not significantly different at 12 weeks (17.3 versus 9.1 percent; RD, 8.2; 95 percent CI, –0.1 to 16.6) but was significantly greater at 24 weeks (20.5 versus 9.9 percent; RD, 10.6; 95 percent CI, 1.8 to 19.4). Adverse events were common for all groups (nicotine e-cigarette with counseling, 94 percent; non-nicotine e-cigarette with counseling, 93 percent; counseling only, 73 percent); cough (64 percent) and dry mouth (53 percent) were the most frequently reported.

"Trial interpretation is limited by early termination and inconsistent findings for nicotine and nonnicotine e-cigarettes, suggesting further research is needed," the authors write.

Two authors disclosed financial ties to Pfizer.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

© 2021 HealthDay. All rights reserved.

Posted: November 2020

Read this next

USPSTF Affirms Evidence-Based Methods for Smoking Cessation

TUESDAY, Jan. 19, 2021 -- The U.S. Preventive Services Task Force (USPSTF) concludes that there is substantial net benefit for behavioral and pharmacological therapies for smoking...

Smokers More Likely to Report Symptoms Suggestive of COVID-19

FRIDAY, Jan. 15, 2021 -- Current smokers are more likely to report symptoms suggesting a diagnosis of COVID-19, according to a study published online Jan. 6 in Thorax. Nicholas...

Causal Link Suggested for Smoking, Subarachnoid Hemorrhage

THURSDAY, Jan. 14, 2021 -- Evidence suggests a causal link between smoking and the risk for subarachnoid hemorrhage (SAH), according to a study published online Jan. 14 in...

More News Resources

Subscribe to our Newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of in your inbox.