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ATS: Lower ARDS Mortality at High-Volume Intensive Care Units

TUESDAY, May 23, 2017 -- For patients with acute respiratory distress syndrome (ARDS), mortality is lower in high-volume intensive care units (ICUs), according to a study presented at the annual meeting of the American Thoracic Society, held from May 19 to 24 in Washington, D.C.

Martin Dres, M.D., from AP-HP, Groupe Hospitalier Pitié-Salpêtrière Charles Foix in Paris, and colleagues collected data on 316,000 individual ICU stays at 35 ICUs between 2000 and 2014, including 18,022 stays related to ARDS.

The researchers found that the prevalence of ARDS in the ICU was 8.3 percent overall. ARDS severity, measured using the Simplified Acute Physiology Score (SAPS2), increased during this period (52 to 58), while decreases were seen in ICU and hospital mortality (57.9 to 45.5 and 59.1 to 48.4 percent, respectively). Compared with low- and moderate-volume ICUs, high-volume ICUs had significantly higher SAPS2 (61 versus 53 and 56, respectively). High- versus low- and moderate-volume ICUs were characterized by lower ICU mortality (51.5 versus 54.3 and 55.2 percent, respectively) and lower hospital length of stay (15 versus 18 and 17 days, respectively). Compared with low- and moderate-volume ICUs, mortality was lower in high-volume ICUs (odds ratio, 0.72).

"Further studies are warranted to confirm and delineate our results and determine whether regionalization of patients with ARDS should be recommended," Dres said in a statement.

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Posted: May 2017