Skip to Content

ASA: Delays in Hospital Care After Arrival Worsen Stroke Outcomes

TUESDAY, March 16, 2021 -- Postarrival care delays are strongly associated with worse endovascular thrombectomy (EVT) patient outcomes in the early postarrival time period, according to research presented at the American Stroke Association International Stroke Conference, held virtually from March 17 to 19.

Mayank Goyal, M.D., Ph.D., from the University of Calgary in Alberta, Canada, and colleagues pooled patient-level data from participants in the Highly Effective Reperfusion Evaluated in Multiple Endovascular Stroke trials. The analysis included early-treated patients (last known well [LKW]-to-puncture of four hours or less) from all seven randomized controlled trials of stent retriever thrombectomy devices (entirely or predominantly) versus medical therapy.

The researchers found that among the 781 EVT-treated patients overall, 406 (52.0 percent) were treated within four hours of LKW, with a median time of 188 minutes for LKW-to-door and 105 minutes for door-to-puncture. Substantial reperfusion was achieved among 295 of 372 individuals, and among them, door-to-reperfusion time was a median 145 minutes. Care process delays were more strongly associated with worse clinical outcomes in the door-to-puncture and door-to-reperfusion periods than for the LKW-to-door timeframe. For each 10-minute delay in door-to-puncture time versus LKW-to-door time, the amount of healthy life-years lost was 1.8 versus 0.0 months, respectively (P < 0.0001). Each 1-second delay in door-to-puncture time and door-to-reperfusion time was associated with 2.2 hours and 2.1 hours of healthy life-years lost, respectively.

"Fast, urgent delivery of stroke care is crucial for all stroke patients in order to reduce the risk of death and serious disability," a coauthor said in a statement.

Press Release

More Information

© 2021 HealthDay. All rights reserved.

Read this next

Traumatic Brain Injury Ups Risk for Future Stroke

WEDNESDAY, April 21, 2021 -- Traumatic brain injury (TBI) is an independent risk factor for stroke, according to a review published online April 4 in the International Journal of...

Longitudinal Study Tracks High Blood Pressure, Stroke Risk

WEDNESDAY, April 21, 2021 -- For young and middle-aged adults, hypertension at baseline, at age 30 years, and at age 40 years is associated with an increased risk for stroke,...

Sex Disparities in COVID-19 Deaths Not Seen Across Race

WEDNESDAY, April 21, 2021 -- Sex disparities in COVID-19 mortality do not hold across racial groups, according to a study published online April 5 in the Journal of General...

More News Resources

Subscribe to our Newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.