Skip to Content

Antibiotic Therapy Before Age 2 May Affect Child Health

TUESDAY, Nov. 17, 2020 -- Exposure to antibiotics in the first two years of life is associated with an increased risk for several health conditions during childhood, according to a study published online Nov. 15 in the Mayo Clinic Proceedings.

Zaira Aversa, M.D., Ph.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues conducted a population-based cohort study involving children born in Olmsted County, Minnesota, between Jan. 1, 2003, and Dec. 31, 2011, to examine the impact of antibiotic exposure in the first two years of life.

Data were included for 14,572 children (7,026 girls and 7,546 boys); during the first two years of life, 70 percent received at least one antibiotic prescription. The researchers identified associations between early antibiotic exposure and an increased risk for childhood-onset asthma, allergic rhinitis, atopic dermatitis, celiac disease, overweight, obesity, and attention-deficit/hyperactivity disorder (hazard ratios ranging from 1.20 to 2.89). The number, type, and timing of antibiotic exposure influenced the associations. The probability of having combinations of conditions was higher for children exposed to antibiotics, especially when given multiple prescriptions.

"The findings from Olmsted County provide evidence for broad and delayed effects of early-life antibiotic exposures, and should change doctors' practices in how often they prescribe antibiotics, especially for mild conditions," a coauthor said in a statement.

Abstract/Full Text

© 2021 HealthDay. All rights reserved.

Posted: November 2020

Read this next

FDA: All Alcohol-Based Hand Sanitizers From Mexico on 'Import Alert'

WEDNESDAY, Jan. 27, 2021 -- All alcohol-based hand sanitizers from Mexico have been put on "import alert" until their safety can be assessed, the U.S. Food and Drug Administration...

COVID-19 Antibody Treatments Exceed Expectations in Early Trials

WEDNESDAY, Jan. 27, 2021 -- Promising new data on two antibody cocktails suggest these therapies can keep COVID-19 patients out of the hospital and even prevent illness altogether...

Many Adults Do Not See Link Between Racism, Poorer Health

WEDNESDAY, Jan. 27, 2021 -- Less than half of U.S. adults see a connection between systemic racism and poorer health outcomes, according to a report released Jan. 13 by the RAND...

More News Resources

Subscribe to our Newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of in your inbox.