Skip to Content

ACR: Corticosteroid Injections Do Not Speed Progression of Knee OA

FRIDAY, Nov. 13, 2020 -- For patients with knee osteoarthritis (OA), corticosteroid injections (CSIs) do not speed progression compared with hyaluronic acid injections (HAI), according to a study presented at ACR Convergence, the annual meeting of the American College of Rheumatology, held virtually from Nov. 5 to 9.

Justin J. Bucci, M.D., from the Boston University School of Medicine, and colleagues used two cohort studies of knee OA to look at rates of X-ray progression and total knee replacement (TKR) among CSI or HAI recipients. Visits were performed every 12 and 30 months in the two cohorts and included knee X-rays and questions about HAI or CSI in the previous six months.

A total of 792 knees were analyzed, of which 647 and 145 reported CSI and HAI use, respectively. CSI and HAI were reported at more than one visit for 124 and 19 knees, respectively. The researchers found that the rate of TKR was increased among those with single exam reports of HAI versus CSI; no difference was seen for those reporting injections at multiple exams, although the absolute numbers were small. In a multivariable analysis, the rates of radiographic progression were similar for CSI and HAI among individuals reporting injections at single or multiple exams.

"We did not find any association between steroid injections and worsening knee OA in our study," Bucci said in a statement. "Patients and clinicians should see this study and feel reassured that these injections are not causing progression of OA or earlier total knee replacement."

Press Release

More Information

© 2021 HealthDay. All rights reserved.

Posted: November 2020

Read this next

Impact of Antidepressants Examined in Back Pain, Osteoarthritis

THURSDAY, Jan. 21, 2021 -- Serotonin-noradrenaline reuptake inhibitors (SNRIs) have a small and not clinically important effect on back pain, but may have a clinically important...

Flat, Flexible No Better Than Stable, Supportive Shoes for Knee OA

TUESDAY, Jan. 12, 2021 -- For patients with knee osteoarthritis, flat, flexible shoes are not superior to stable, supportive shoes, according to a study published online Jan. 12...

Knee Osteoarthritis Symptoms Improved With Stepped Care

TUESDAY, Dec. 29, 2020 -- A stepped exercise program results in modest improvements for symptoms of knee osteoarthritis, according to a study published online Dec. 29 in the...

More News Resources

Subscribe to our Newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of in your inbox.