Generic Name: benzoyl peroxide and sodium hyaluronate topical (BEN zoe il per OX ide and SOE dee um HYE al ure ON ate)
Brand Name: Zacare
What is benzoyl peroxide and sodium hyaluronate topical?
Benzoyl peroxide has an antibacterial effect. It also has a mild drying effect, which allows excess oils and dirt to be easily washed away from the skin.
Sodium hyaluronate is a lubricant that restores moisture to the skin.
Benzoyl peroxide and sodium hyaluronate topical (for the skin) is a combination medicine used to treat severe acne along with dry or scaly skin.
Benzoyl peroxide and sodium hyaluronate topical may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about benzoyl peroxide and sodium hyaluronate topical?
Benzoyl peroxide can cause a rare but serious allergic reaction or severe skin irritation. Stop using this medicine and get emergency medical help if you have: hives, itching; difficult breathing, feeling light-headed; or swelling of your face, lips, tongue, or throat.
What should I discuss with my healthcare provider before using benzoyl peroxide and sodium hyaluronate topical?
You should not use this medicine if you are allergic to benzoyl peroxide or sodium hyaluronate.
FDA pregnancy category C. It is not known whether benzoyl peroxide and sodium hyaluronate topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether benzoyl peroxide and sodium hyaluronate topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Do not use this medicine on a child younger than 12 years old without the advice of a doctor.
How should I use benzoyl peroxide and sodium hyaluronate topical?
This medication comes as a kit containing benzoyl peroxide lotion and sodium hyaluronate gel.
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Benzoyl peroxide can cause rare but serious allergic reactions or severe skin irritation. Before you start using this medicine, you may choose to apply a "test dose" to see if you have a reaction. Apply a very small amount of the medicine to 1 or 2 small acne areas every day for 3 days in a row. If there is no reaction, begin using the full prescribed amount on the 4th day.
Shake the benzoyl peroxide lotion well just before each use.
Wet the skin before applying the benzoyl peroxide cleansing lotion. Work the lotion into a lather and rinse thoroughly. Gently pat the skin dry.
During your first week of treatment, wash the affected skin with the benzoyl peroxide lotion once daily. After the first week, wash the skin twice daily.
The sodium hyaluronate gel may be applied 2 or 3 times daily. Follow your doctor's instructions. Apply a liberal amount of the gel and rub it in thoroughly.
Do not cover the treated skin area unless your doctor tells you to.
It may take up to 3 weeks before your symptoms improve. The best results may be seen after 8 to 12 weeks of use. Keep using the medication as directed and tell your doctor if your symptoms do not improve.
Store at room temperature away from moisture and heat. Keep the lotion bottle and ointment tube tightly closed when not in use.
What happens if I miss a dose?
Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
An overdose of benzoyl peroxide and sodium hyaluronate topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.
What should I avoid while using benzoyl peroxide and sodium hyaluronate topical?
Do not use this medicine on open wounds or on sunburned, windburned, dry, chapped, or irritated skin.
Do not take by mouth. Topical medicine is for use only on the skin.
Avoid getting this medicine in your eyes.
If this medicine gets in your eyes, nose, or mouth or on your lips, rinse with water.
Avoid exposure to sunlight or tanning beds. Use sunscreen (SPF 30 or higher) over treated skin areas when you are outdoors.
Benzoyl peroxide can bleach hair or fabrics. Avoid allowing this medicine to come into contact with your hair or clothing.
Do not use other medicated skin products unless your doctor has told you to.
Benzoyl peroxide and sodium hyaluronate topical side effects
Benzoyl peroxide can cause a rare but serious allergic reaction or severe skin irritation. These reactions may occur just a few minutes after you apply the medicine, or within a day or longer afterward.
Stop using this medicine and get emergency medical help if you have any of these signs of an allergic reaction: hives, itching; difficult breathing, feeling light-headed; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have severe stinging or burning of your skin.
Common side effects may include:
redness or peeling of treated skin;
mild burning or stinging; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect benzoyl peroxide and sodium hyaluronate topical?
It is not likely that other drugs you take orally or inject will have an effect on topically applied benzoyl peroxide and sodium hyaluronate. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
Where can I get more information?
- Your pharmacist can provide more information about benzoyl peroxide and sodium hyaluronate topical.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 3.02.
Date modified: March 15, 2017
Last reviewed: July 23, 2014