Generic Name: pentazocine (pen TAZ oh seen)
Brand Name: Talwin
What is Talwin (pentazocine)?
Pentazocine is an opioid pain medication. An opioid is sometimes called a narcotic.
Pentazocine is used to treat moderate to severe pain. It is also used as part of anesthesia for surgery.
Pentazocine may also be used for purposes not listed in this medication guide.
What is the most important information I should know about Talwin (pentazocine)?
Pentazocine can slow or stop your breathing. Never use this medicine in larger amounts, or for longer than prescribed. Pentazocine may also be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction.
Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.
What should I discuss with my health care provider before using Talwin (pentazocine)?
You should not use pentazocine if you are allergic to it.
To make sure pentazocine is safe for you, tell your doctor if you have:
any type of breathing problem or lung disease;
asthma or sulfite allergy;
a history of head injury, brain tumor, or mental illness;
a history of alcoholism or drug addiction (pentazocine may be habit-forming);
a seizure disorder;
high blood pressure, heart disease, history of recent heart attack;
liver or kidney disease; or
Some medicines can interact with pentazocine and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.
It is not known whether this medicine will harm an unborn baby. If you use pentazocine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether pentazocine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How is Talwin (pentazocine)given?
Pentazocine is injected under the skin or into a muscle, or into a vein through an IV. A healthcare provider will give you this injection.
Pentazocine may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Selling or giving away pentazocine is against the law.
Pentazocine is usually given only for a short time.
You may have unpleasant withdrawal symptoms if you stop using pentazocine suddenly after long-term use. If you receive more than a single dose, ask your doctor how to avoid withdrawal symptoms when you stop using pentazocine.
What happens if I miss a dose?
Since pentazocine is used when needed and given by a healthcare professional, you are not likely to miss a dose.
What happens if I overdose?
Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid while using Talwin (pentazocine)?
Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with pentazocine.
Pentazocine may impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you. Dizziness or severe drowsiness can cause falls or other accidents.
Talwin (pentazocine) side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
pain, burning, irritation, or skin changes where the injection was given;
weak or shallow breathing;
painful or difficult urination; or
a light-headed feeling, like you might pass out.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Pentazocine is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.
Common side effects may include:
headache, dizziness, drowsiness;
anxiety, feelings of extreme happiness;
dry mouth, blurred vision, ringing in your ears.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Talwin (pentazocine)?
Some medicines can cause unwanted or dangerous effects when used with pentazocine. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.
Using this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking a sleeping pill, other narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
Other drugs may interact with pentazocine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
More about Talwin (pentazocine)
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Where can I get more information?
- Your doctor or pharmacist can provide more information about pentazocine.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 2.04.
Date modified: October 14, 2016
Last reviewed: March 30, 2016