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Taltz Autoinjector

Generic Name: ixekizumab (IX ee KIZ ue mab)
Brand Name: Taltz Autoinjector, Taltz Prefilled Syringe

What is Taltz Autoinjector?

Taltz Autoinjector is an immunosuppressant that reduces the effects of a chemical substance in the body that can cause inflammation.

Taltz Autoinjector is used to treat moderate to severe plaque psoriasis (raised, silvery flaking of the skin) in adults. This medicine is also used to treat active psoriatic arthritis in adults.

Taltz Autoinjector may also be used for purposes not listed in this medication guide.

Important Information

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use Taltz Autoinjector if you are allergic to it.

To make sure Taltz Autoinjector is safe for you, tell your doctor if you have:

Your doctor may perform tests to make sure you do not have tuberculosis or other infections.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether Taltz Autoinjector passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Taltz Autoinjector is not approved for use by anyone younger than 18 years old.

How is ixekizumab given?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Taltz Autoinjector is injected under the skin. You may be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of used needles and syringes.

This medicine is not used daily. Your first dose may be given as 2 injections at the same time. Later doses are then given once every 2 to 4 weeks.

The timing of your injections will depend on the condition being treated. Follow your doctor's dosing instructions very carefully.

Your care provider will show you the best places on your body to inject Taltz Autoinjector. Use a different place each time you give an injection. Do not inject into the same place two times in a row. Do not give an injection into a skin area with active psoriasis, or skin that is red, bruised, or tender.

Taltz Autoinjector should appear as a clear to light-yellow liquid. Do not use the medicine if it looks cloudy or has particles in it. Call your pharmacist for new medication.

Do not shake the syringe or injection pen.

Taltz Autoinjector can weaken (suppress) your immune system, and you may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, weakness, cold or flu symptoms, skin sores, diarrhea, frequent or recurring illness).

Use a disposable needle and syringe only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.

Store this medicine in the original container in a refrigerator. Protect from light and do not freeze. Do not use the medicine if it has become frozen.

Before injecting your dose, take the injection pen or prefilled syringe out of the refrigerator and leave it at room temperature for 30 minutes. Do not heat the medicine in a microwave or under hot water, and do not leave it in direct sunlight.

Each single-use injection pen or prefilled syringe is for one use only. Throw it away after one use, even if there is still medicine left inside.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Taltz Autoinjector?

Do not share this medicine with another person, even if they have the same symptoms you have.

Do not receive a "live" vaccine while using Taltz Autoinjector. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

Taltz Autoinjector side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • fever, chills, sweating, muscle pain, weight loss;

  • diarrhea (may be bloody), stomach cramps;

  • painful skin sores;

  • cough, shortness of breath, cough with red or pink mucus;

  • sores or white patches in your mouth or throat (yeast infection or "thrush");

  • increased urination, pain or burning when you urinate;

  • eye swelling, redness, crusting or drainage (may be signs of infection); or

  • signs of a fungal infection (rash or red patches, itching, burning, cracked skin, hair loss).

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Taltz Autoinjector?

Other drugs may interact with ixekizumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about Taltz Autoinjector.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 2.01.

Date modified: March 06, 2018
Last reviewed: January 09, 2018