Skip to Content

Somatuline Depot

Generic Name: lanreotide (lan REE oh tide)
Brand Name: Somatuline Depot

What is lanreotide?

Lanreotide is a man-made protein similar to a hormone in the body called somatostatin. Lanreotide lowers many substances in the body such as insulin and glucagon (involved in regulating blood sugar), growth hormone, and chemicals that affect digestion.

Lanreotide is used in adults to treat:

  • acromegaly that cannot be treated with surgery or radiation;

  • carcinoid syndrome; or

  • a certain type of pancreatic or digestive tract tumor that may spread to other parts of the body.

Lanreotide is sometimes given after other treatments have failed.

Lanreotide may also be used for purposes not listed in this medication guide.

Important Information

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use lanreotide if you are allergic to it.

To make sure lanreotide is safe for you, tell your doctor if you have ever had:

  • gallbladder disease;

  • diabetes (your diabetes medicine may need to be adjusted);

  • liver or kidney disease;

  • heart disease; or

  • a thyroid disorder.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breast-feed while using lanreotide and for at least 6 months after your last dose.

How is lanreotide given?

Lanreotide is injected under the skin.

A healthcare provider will give you this injection.

Lanreotide is usually given once every 4 weeks.

Call your doctor if your symptoms do not improve, or if they get worse.

Your blood sugar may need to be checked often, and you may need other blood tests at your doctor's office.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your lanreotide injection.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using lanreotide?

Lanreotide can make it harder for your body to absorb other medicines you take by mouth. Ask your doctor about the best schedule for taking all of your needed medicines.

Lanreotide side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • slow heartbeats;

  • low blood sugar--headache, hunger, sweating, irritability, dizziness, nausea, fast heart rate, and feeling anxious or shaky;

  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor, headache, blurred vision;

  • increased blood pressure--severe headache, blurred vision, pounding in your neck or ears, anxiety, nosebleed; or

  • signs of a gallbladder problem--sudden severe pain in your upper stomach spreading to your back or shoulder (may occur after meals or at night), pain when breathing, nausea, vomiting, loss of appetite, fever, chills, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • nausea, vomiting, stomach pain;

  • diarrhea, gas;

  • muscle or joint pain;

  • headache, dizziness; or

  • pain, itching, or a hard lump where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect lanreotide?

Tell your doctor about all your current medicines and any you start or stop using, especially:

This list is not complete. Other drugs may interact with lanreotide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

  • Your pharmacist can provide more information about lanreotide.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 5.01.

Date modified: March 06, 2018
Last reviewed: January 26, 2018