What is Praluent Syringe?
Praluent Syringe is a human monoclonal antibody. It works by helping the liver reduce levels of "bad" cholesterol (low-density lipoprotein, or LDL) circulating in your blood.
Praluent Syringe is used together with a low-fat diet and a "statin" medication in people with heterozygous familial hypercholesterolemia (an inherited type of high cholesterol). This condition can cause high blood levels of LDL cholesterol, and can also cause plaque to build up inside your arteries.
Praluent Syringe may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not use Praluent Syringe if you are allergic to it.
To make sure Praluent Syringe is safe for you, tell your doctor about all your medical conditions or allergies.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether Praluent Syringe passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Praluent Syringe is not approved for use by anyone younger than 18 years old.
How should I use Praluent Syringe?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Praluent Syringe is injected under the skin, once every 2 to 4 weeks. You may be shown how to use injections at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles and syringes.
Your care provider will show you the best places on your body to inject Praluent Syringe. Use a different place each time you give an injection. Do not inject into the same place two times in a row.
If you use Praluent Syringe only once every 4 weeks, you will give yourself 2 separate injections at the same time. Use a new syringe or injection pen for each injection. Give each injection into a different place on your body.
Each single-use injection pen or prefilled syringe is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting your dose. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.
Store this medicine in the refrigerator, do not freeze. Protect from light and high heat.
Take the medicine out of the refrigerator and allow it to reach room temperature for 30 to 40 minutes before injecting your dose. Do not heat an injection pen or prefilled syringe, and do not leave the pen at room temperature for longer than 24 hours.
Do not shake this medicine. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.
While using Praluent Syringe, you may need frequent blood tests.
You should not stop using Praluent Syringe without your doctor's advice, or your LDL cholesterol levels may increase.
Praluent Syringe is only part of a complete treatment program that also includes diet, statin medication, and regular blood testing. Follow your doctor's instructions very closely.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
What happens if I miss a dose?
If you inject once every 2 weeks: Use the missed dose within 7 days after the injection was due. Then go back to your original schedule and use the medicine again when your next scheduled dose is due.
If you inject once every 4 weeks: Use the missed dose within 7 days after the injection was due. Then give the next injection 4 weeks later to start a new schedule based on the date you used the missed injection.
Skip the missed dose if you are more than 7 days late for the injection. Do not use extra medicine to make up a missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using Praluent Syringe?
Do not inject Praluent Syringe into skin that is sunburned, infected, swollen, or otherwise irritated.
Praluent Syringe side effects
Get emergency medical help if you have signs of an allergic reaction: hives, severe itching; difficult breathing; swelling of your face, lips, tongue, or throat.
Common side effects may include:
redness, itching, soreness, or swelling where an injection was given;
flu symptoms; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Praluent Syringe?
Other drugs may interact with alirocumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
More about Praluent (alirocumab)
- Side Effects
- During Pregnancy
- Dosage Information
- Support Group
- Pricing & Coupons
- 33 Reviews – Add your own review/rating
- Drug class: PCSK9 inhibitors
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about Praluent Syringe.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 2.01.
Date modified: March 06, 2018
Last reviewed: July 12, 2017