Medically reviewed on November 13, 2017
What is Ortho D?
Folic acid is vitamin B9, or folate. Vitamin B9 helps your body produce and maintain new cells. Folic acid also helps prevent several types of birth defects when taken by pregnant women.
Ortho D is a combination medicine used in people who do not get enough of these vitamins in their diets to maintain adequate health.
Ortho D may also be used for purposes not listed in this medication guide.
You should not take Ortho D if you have had an allergic reaction to vitamin D, or if you have high levels of calcium or vitamin D in your body, or any condition that makes it hard for your body to absorb nutrients from food (malabsorption).
Before taking this medicine
You should not use this medicine if you have ever had an allergic reaction to vitamin D or folic acid, or if you have:
high levels of vitamin D in your body (hypervitaminosis D);
high levels of calcium in your blood (hypercalcemia); or
any condition that makes it hard for your body to absorb nutrients from food (malabsorption).
Folic acid is sometimes used in combination with other medications to treat pernicious anemia. However, Ortho D will not treat Vitamin B12 deficiency and will not prevent possible damage to the spinal cord. Take all of your medications as directed by your doctor.
To make sure Ortho D is safe for you, tell your doctor if you have ever had:
vitamin B12 deficiency (pernicious anemia);
kidney disease; or
a thyroid disorder.
Too much vitamin D could harm an unborn baby, and your dose needs may be different during pregnancy. Tell your doctor if you are pregnant or if you become pregnant while taking cholecalciferol.
Cholecalciferol can pass into breast milk and may cause side effects in the nursing baby. Tell your doctor if you are breast-feeding.
Do not give Ortho D to a child without medical advice. Your child's dose will depend on age, weight, diet, and other factors.
How should I take Ortho D?
Follow all directions on your prescription label. Use only the recommended dose of cholecalciferol and folic acid. Do not use Ortho D in larger or smaller amounts or for longer than recommended.
Ortho D may be only part of a complete program of treatment that also includes dietary changes and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.
Learn about the foods you should eat to make sure you get enough calcium and vitamin D in your diet. Your Ortho D dose may need to be adjusted as you make changes to your diet.
Store at room temperature away from moisture, heat, and light.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of vitamin D can cause serious or life-threatening side effects.
Overdose symptoms may include nausea, loss of appetite, thirst, urinating more or less than usual, body aches, stiffness, confusion, or irregular heartbeats.
What should I avoid while taking Ortho D?
Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking Ortho D.
Ortho D side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop taking Ortho D and call your doctor at once if you have:
nausea, vomiting, decreased appetite;
Less serious side effects may be more likely, and you may have none at all.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Ortho D?
Certain medications can make it harder for your body to absorb vitamin D. If you take other medications, take them at least 2 hours before or 2 hours after you take Ortho D.
Other drugs may interact with cholecalciferol and folic acid, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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