Generic Name: griseofulvin (GRIS ee oh FUL vin)
Brand Name: Grifulvin V, Gris-PEG
What is Gris-PEG (griseofulvin)?
Griseofulvin is an antifungal medication that fights infections caused by fungus.
Griseofulvin is used to treat infections such as ringworm, athlete's foot, jock itch, and fungal infections of the scalp, fingernails, or toenails.
Griseofulvin may also be used for purposes not listed in this medication guide.
What is the most important information I should know about Gris-PEG (griseofulvin)?
You should not use griseofulvin if you have porphyria or liver failure.
Taking griseofulvin during the first 3 months of pregnancy may harm the unborn baby.
What should I discuss with my healthcare provider before taking Gris-PEG (griseofulvin)?
You should not use griseofulvin if you are allergic to it, or if you have:
porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system); or
if you are pregnant or may become pregnant.
To make sure griseofulvin is safe for you, tell your doctor if you have:
an allergy to penicillin; or
if you take a blood thinner such as warfarin (Coumadin, Jantoven).
FDA pregnancy category X. This medicine can harm an unborn baby or cause birth defects. Do not use griseofulvin if you are pregnant. Tell your doctor right away if you become pregnant during treatment.
Griseofulvin may make birth control pills less effective. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy while taking griseofulvin.
It is not known whether griseofulvin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Griseofulvin should not be given to a child younger than 2 years old, or a child who weighs less than 35 pounds.
How should I take Gris-PEG (griseofulvin)?
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
To make swallowing easier, you may crush the Gris-PEG tablet and sprinkle the medicine into a spoonful of applesauce. Swallow right away without chewing. Do not save the mixture for later use.
Use this medicine for the full prescribed length of time. It may take up several weeks before your symptoms improve. Nail infections can take several months to clear completely.
Griseofulvin will not treat a bacterial or fungal infection, or a viral infection such as the flu or a common cold.
If you use this medicine long-term, you may need frequent medical tests at your doctor's office.
Store at room temperature away from moisture, heat, and light.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Gris-PEG (griseofulvin)?
Avoid exposure to sunlight or tanning beds. Griseofulvin can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Drinking alcohol while taking griseofulvin can cause unpleasant side effects.
Gris-PEG (griseofulvin) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
fever, chills, flu symptoms, white patches or sores inside your mouth or on your lips;
confusion, trouble with daily activities;
liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
lupus-like syndrome--joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color; or
severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
nausea, vomiting, upset stomach, diarrhea;
headache, tired feeling;
sleep problems (insomnia); or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Gris-PEG (griseofulvin)?
Other drugs may interact with griseofulvin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
More about Gris-PEG (griseofulvin)
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about griseofulvin.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 6.01.
Date modified: January 10, 2017
Last reviewed: December 01, 2014